EDITOR—The use of hair as a biopsy tissue has been considered for some time. For instance, in the case of breast cancer, raised zinc levels in head hair have been reported. 1 Besides, x ray diVraction patterns of hair are rich and have attracted much attention for 70 years. 2 However, its potential use as a diagnostic indicator of disease was only suggested a short time ago. 3 Most recently, Ja...

BACKGROUND Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disease of unknown etiology that causes arrhythmias, heart failure, and sudden death. Diagnosis can be difficult, and this hampers investigation of its molecular basis. Forms of ARVC in which gene penetrance and disease expression are greater should facilitate genetic study. We undertook a clinical and genetic i...

Background: Alopecia Areate (AA) is a recurrent non-scarring patchy hair loss of autoimmune origin in a genetically susceptible individual although environmental factors may be contributory. The aim of this study is to evaluate serum iron and ferritin levels in patients with AA. Methods: Fifty patients of AA and 50 age and sex matched control subjects without any hair loss were studied. Results...

Seventeen patients with polycystic ovarian disease (peOD) were treated by laparoscopic ovarian electrocauterization (LEC). Ten were admitted to hospital for infertility, four for hirsutism, two for severe scalp hair loss, and one for abnormal uterine bleeding. Four of the patients were virgins. We had 50% (5 of 10) pregnancies and 88% (15 of 17) showing a decline in testosterone levels aft...

HYPOTHESIS The aim of this study was to create a more dynamic animal model of Ménière's disease combining multiple causes, such as the role of endocrine factors and endolymphatic sac dysfunction, that may mimic the fluctuant characteristics of Ménière's disease. BACKGROUND Endolymphatic hydrops remains to be considered a pathologic substrate in the etiology of Ménière's disease. The classic g...

manganese and cobalt concentrations in hair and nail were determined by flame atomic absorption spectrophotometer (aas).the mean manganese in hair and nail were 0.54 â± 0.35mg/g and 0.68 â± 0.30mg/g while the mean cobalt in hair and nail were 0.30 â± 0.24mg/g and 0.460.37mg/g respectively. a progressive increase in cobalt concentrations in hair and nails with age indicated no significant differ...

OBJECTIVES To better categorize the epidemiologic profile, clinical features, and disease associations of loose anagen hair syndrome (LAHS) compared with other forms of childhood alopecia. DESIGN Retrospective survey. SETTING Academic pediatric dermatology practice. Patients Three hundred seventy-four patients with alopecia referred from July 1, 1997, to June 31, 2007. MAIN OUTCOME MEASUR...

A number of different modalities of surgical treatment for axillary hidradenitis suppurativa have been suggested. This study compares three different methods of surgical excision. Fifty-nine patients (94 axillae) were treated over a 14-year period. There were 42 females and 17 males with an average age of 32 years (range 16-65 years). Twenty-six axillae had excision of only the diseased skin an...

Pemphigus vulgaris is an autoimmune blistering disease that commonly involves the scalp. Lesions of pemphigus vulgaris that persist on the scalp for a long period may be accompanied by tufted hair folliculitis. Only two previous accounts of tufted hair folliculitis developing in a lesion of pemphigus vulgaris have been reported. We report a 51-year-old-man with erosions and clusters of hair on ...

Changes in the homeostasis of metals and microelements have been demonstrated in Parkinson's disease, whose etiology includes both a genetic and environmental basis. We studied the difference of microelements in the hair of Parkinson's disease subjects (n = 46) compared with healthy controls (n = 24). Hair was chosen as a representative matrix to measure microelements, since it is a vehicle of ...