Objectives Good communication between clinicians and pathologists is a vital element in the diagnostic process, poor can adversely affect patient care. There lack of research about oral maxillofacial pathology. This narrative review explores different aspects quality pathologists, with focus on diagnosis diseases. Study design An electronic search was carried out MEDLINE/PubMe...

AbstractObjectives This study presents the design of an integrated, proactive palliative care pathway covering full cycle and evaluates its effects using 3 types outcomes: (1) physician-reported outcomes, (2) outcomes reported by family, (3) (utilization of) health outcomes. Design A clustered, partially controlled before-after with a multidisciplinary integrated as m...

Importance Previous studies have shown reductions in self-reported physical activity levels children associated with implementation of COVID-19 mitigation measures, and data on objectively assessed health parameters are limited. Objective To examine the association measures changes cardiorespiratory fitness (CRF) body mass index (BMI) among primary schoolchildren. Design, ...

Histone H3.Y is a primate-specific, distant H3 variant. It is evolutionarily derived from H3.3, and may function in transcription regulation. However, the mechanism by which H3.Y regulates transcription has not been elucidated. In the present study, we determined the crystal structure of the H3.Y nucleosome, and found that many H3.Y-specific residues are located on the entry/exit sites of the n...

B7-H3, first recognized as a co-stimulatory molecule, is abnormally expressed in cancer tissues and is associated with cancer metastasis and a poor prognosis. However, as an initial event of metastasis, the relationship between the Epithelial-Mesenchymal Transition (EMT ) in cancer cells and B7-H3 has still not been investigated. In this study, we first analyzed B7-H3 expression by immunohistoc...

Although the Ran GTPase-activating protein RanGAP mainly functions in the cytoplasm, several lines of evidence indicate a nuclear function of RanGAP. We found that Schizosaccharomyces pombe RanGAP, SpRna1, bound the core of histone H3 (H3) and enhanced Clr4-mediated H3-lysine 9 (K9) methylation. This enhancement was not observed for methylation of the H3-tail containing K9 and was independent o...

ABSTRACTObjective To adapt and optimize problem adaptation therapy for depression in dementia by grounding it the lives of people with dementia, caregivers clinicians. Methods A person-centered qualitative approach was taken to elicit unique cognitive, psychological social needs relevant intervention. two-stage design used: first involved interviews focus groups ident...

Background: The COVID-19 (C-19) pandemic required swift response from health care organizations to mitigate spread and impact. A large integrated network rapidly deployed operationalized multiple access channels the community, allowing assessment triage occur virtually. These were characterized by implementation of virtual models, including asynchronous e-visits video visits for C-19 s...

Abstract Motivation Bayesian networks (BNs) are widely used to model biological from experimental data. Many software packages exist infer BN structures, but the chance of getting trapped in local optima is a common challenge. Some recently developed Markov Chain Monte Carlo (MCMC) samplers called Neighborhood sampler (NS) and Hit-and-Run (HAR) sampler, have shown great potent...

AbstractIntroduction Mattresses in the radiology department tend to be an overlooked aspect of imaging equipment. This paper evaluates radiation attenuation characteristics mattresses and effect they have on image quality. Methods Thirteen (from new 20 years age) were evaluated. Incident air kerma (IAK) was measured two conditions, with without mattress over a range e...