Multiple system atrophy (MSA) is a rare, yet rapidly-progressive neurodegenerative disease that presents clinically with autonomic failure in combination with parkinsonism or cerebellar ataxia. The definitive neuropathology differentiating MSA from Lewy body diseases is the presence of α-synuclein aggregates in oligodendrocytes (called glial cytoplasmic inclusion or GCI) rather than the fibrill...

High-pressure phase equilibrium and volumetric properties of highly asymmetric mixtures related to reservoir fluids are critical the development high-pressure high-temperature (HPHT) reservoirs. However, there is a lack relevant data accurate modeling tools. In this work, we prepared pseudo-binary methane (CH4) + stock tank oil (STO) systematically measured their densities at temperatures from ...

The primary therapeutic target for diabetes management is the achievement of good glycemic control, of which glycated hemoglobin (HbA1c) remains the standard clinical marker. However, glycemic variability (GV; the amplitude, frequency, and duration of glycemic fluctuations around mean blood glucose) is an emerging target for blood glucose control. A growing body of evidence supports GV as an in...

Total sixty four straight run broiler chicks of two daysold were fed a control diet and diet supplemented with Fungi inhibitor (FI): Gentian violet (GV), Copper sulphate (CS), GV+CSto evaluate the effect of dietary FI on the performance characteristics of broiler. The levels of GV, CS and GV+CS were 0.05%, 0.06% and 0.025%+0.06%, respectively. Dietary FI did not alter the growth rate, feed inta...

Definition 1.1 (see [1]). A triple (X ,M,∗), where X is an arbitrary set, ∗ is a continuous t-norm, andM is a fuzzy set on X2× (0,∞), is said to be a fuzzy metric space (in the sense of George and Veeramani) if the following conditions are satisfied for all x, y ∈ X and s, t > 0: (GV-1) M(x, y, t) > 0; (GV-2) M(x, y, t)= 1 if and only if x = y; (GV-3) M(x, y, t)=M(y,x, t); (GV-4) M(x, y,·) is c...

BACKGROUND AND PURPOSE Blepharospasm (BSP) and apraxia of eyelid opening (AEO) have been reported as dystonia related with parkinsonism. However, systematic analysis of clinical characteristics of BSP and AEO in parkinsonism has been seldom reported. To investigate the clinical characteristics of BSP and AEO in parkinsonism and to find out the clinical significance to differentiate parkinsonism...

Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) are an adult-onset progressive neurodegenerative disorder that are known to display diverse clinical features and disease progression. We aim to characterize the clinical features and disease progression in patients with MSA and PSP by using a number of relevant disability milestones in Koreans. Forty-one patients with MSA a...

The genome of the Choristoneura occidentalis granulovirus (ChocGV) isolated from the western spruce budworm, Choristoneura occidentalis, was sequenced completely. It was 104,710 bp long, with a 67.3% A+T content and contained 116 potential open reading frames (ORFs) covering 88.4% of the genome. Of these, 29 ORFs were conserved in all fully sequenced baculovirus genomes, 30 were GV-specific, 53...

Generalized vitiligo (GV) is a complex disease in which patchy depigmentation results from autoimmune loss of melanocytes from affected regions. Genetic analyses of GV span six decades, with the goal of understanding biological mechanisms and elucidating pathways that underlie the disease. The earliest studies attempted to describe the mode of inheritance and genetic epidemiology. Early genetic...

The Babesia bovis MSA-1, MSA-2b and MSA-2c are members of the variable merozoite surface antigen (VMSA) family, they are encoded surface proteins that are proposed to mediate the initial attachment of the merozoite to the host erythrocyte so this protein are targeted for vaccine and drug design. So the aim of this study is to give an outlook for MSA-1, MSA-2b and MSA-2c proteins using bioinform...