The digestive system is critical for maintenance of all multicellular organisms. As the organism ingests food, it must be processed and essential nutrients removed and absorbed into the body prior to expulsion of the waste products. In higher organisms, these steps are handled by a series of specialized organs. In spite of its ultimate complexity, the vertebrate gut develops from a primitive tu...

bacteria play an important role in the initiation and progression of diseases (not only in disease but affect health status of individual). populations of digestive microflora in chicken gut change with age and also affected by diet, stressors, and performance enhancers as well as in disease conditions. the aim of the pre-sent study was to know bacterial makeup in chicken gut, using denaturing ...

The gut mucosa acts as a barrier against microbial invaders, whereas resident commensal and foreign invading bacteria interact intimately with the gut epithelium and influence the host cellular and immune systems. The epithelial barrier serves as an infectious foothold for many bacterial pathogens and as an entry port for pathogens to disseminate into deeper tissues. Enteric bacterial pathogens...

The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remains largely unknown, even though enteritis as well as liver and gallbladder syndrome emerged as a limitation in aquaculture. In this study, we performed integrative bioinformatic...

BACKGROUND The gut microbiota has profound effects on host physiology but local host-microbial interactions in the gut are only poorly characterised and are likely to vary from the sparsely colonised duodenum to the densely colonised colon. Microorganisms are recognised by pattern recognition receptors such as Toll-like receptors, which signal through the adaptor molecule MyD88. METHODS To id...

gut microbiota is formed by ten of trillions of microorganisms with at least 1000 different species of known bacteria. one - third of an individual gut microbiota is common to most people, while two - thirds are specific to him. growing amount of evidence indicates that gut microbiota characteristics may play an important role in mental dysfunctions. molecular mimicry between several key neurop...

The function of the gut microbiome and the bidirectional communication between the gastrointestinal tract (GIT) and the brain is increasingly recognized in health and disease and disruption in its composition is not unique to the autistic pathology. However, the bidirectional communication between the gut and the brain, “the gut-brain/brain-gut axis” in autism has been relatively understudied. ...

Gut microbial communities can greatly affect host health by modulating the host's immune system. For many important insects, however, the relationship between the gut microbiota and immune function remains poorly understood. Here, we test whether the gut microbial symbionts of the honey bee can induce expression of antimicrobial peptides (AMPs), a crucial component of insect innate immunity. We...

The Campylobacter jejuni-host interaction may be affected by the host's gut microbiota through competitive exclusion, metabolites, or modification of the immune response. To understand this interaction, C. jejuni colonization and local immune responses were compared in chickens with different gut microbiota compositions. Birds were treated with an antibiotic cocktail (AT) (experiments 1 and 2) ...