Prevention of arterial thrombotic disorders is a very important socioeconomic challenge. The most convenient way of prevention could be by dietary means. In testing diets for antithrombotic effect, selection of pathologically relevant models of arterial thrombosis is of crucial importance. We demonstrated that the shear-induced platelet-rich thrombosis/thrombolysis in vitro/ex vivo test, Global...

BACKGROUND The second generation antipsychotic (SGA) drugs are widely used in psychiatry due to their clinical efficacy and low incidence of neurological side-effects. However, many drugs in this class cause deleterious metabolic side-effects. Animal models accurately predict metabolic side-effects for SGAs with known clinical metabolic liability. We therefore used preclinical models to evaluat...

Introduction While the vast majority of clinical MRI sequences utilize Cartesian sampling strategies, in a growing number of applications nonCartesian schemes are being employed for a variety of technical reasons. For example, our own motivation is diffusion tensor imaging (DTI) wherein we use spiral trajectories [1], in part because they facilitate efficient self-navigation schemes for artifac...

Amaç: Son yıllarda dünyada ve ülkemizde “Geleneksel Tamamlayıcı Tıp” (GTT) uygulamalarında ürünlerinin kullanımında artış izlenmektedir. Hekimler GTT uygulamalarının gerekliliği, yararları veya olası komplikasyonları konusunda tam bir görüş birliğine sahip değildir. Bu çalışmada çocuk hekimlerinin uygulamaları konusundaki bilgi görüşlerini değerlendirmek amaçlanmıştır.
 
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Previous studies have shown that the clove essential oil concentration of 200 mg/kg did not present toxicity and histopathological changes in liver. Based on evidence presented this study, we decided to evaluate vivo ability a previously developed fermented dairy beverage, tested only vitro, which standard chemical preservative, potassium sorbate, was replaced by (2 μl/ml), be functional food. ...

To assess whether women with gestational diabetes (GDM) should be screened the glucose tolerance test (GTT) instead of challenge (GCT) as primary in next pregnancy. This is an IRB-exempt retrospective cohort study. We included GDM who had a subsequent delivery at our institution from 2004-2020. Patients BMI < 18.5 kg/m2, multifetal gestation, pregestational mellitus and chronic hypertension wer...

Abstract Gradually typed languages are designed to support both dynamically and statically programming styles while preserving the benefits of each. Sound gradually check types at runtime boundary between modules. However, there is much disagreement in gradual typing literature over how enforce complex such as tuples, lists, functions objects. In this paper, we propose a new perspective on desi...

background: methamphetamine (ma) is a potent psychomotor stimulant with high abuse and addictive potential. ma is a neurotoxic drug which is widely abused by females of childbearing age, raising serious public health concerns in terms of exposure of the fetus to the drug. neurotoxic effects of ma on adult are well known, such as dopaminergic nerve terminal degeneration and cell death in regions...

some of the endocrinologic diseases, especially acromegaly, cushing and pheochromocytoma have multiple effects on blood glucose metabolism and regulation in non-diabetic patients. in this retrospective survey, records of patients of tehran medical sciences university hospitals have been reviewd. of 124 acromegals, gtt was performed for 51 patients, being impaired in 18%. to evaluate diabetes, f...