IEEE 802.15.4 protocol is designed for low-rate Wireless Personal Area Networks with very low cost and power consumption. IEEE 802.15.4 provides Guaranteed Time Slots (GTSs) which allow a device to operate on the channel within a portion of the superframe that is dedicated exclusively to that device. The GTSs always appear at the end of the active superframe starting at a slot boundary immediat...

Software architecture plays an important role in the success of modern, large and distributed software systems. For many of the software systems – especially safety-critical ones – it is important to specify their architectures using formal modeling notations. In this case, it is possible to assess different functional and nonfunctional properties on the designed models. Graph Transformation Sy...

BACKGROUND The actin cytoskeleton in podocytes is essential for the maintenance of its normal structure and function. Its disruption is a feature of podocyte foot-process effacement and is associated with proteinuria. α-Actinin-4 in podocytes serves as a linker protein binding the actin filaments of the cytoskeleton. METHODS To investigate the effect of ginseng total saponin (GTS) on the path...

OBJECTIVE To present the current concepts of the clinical phenomenology and natural history of Gilles de la Tourette syndrome (GTS), differential diagnosis with other involuntary movements, its pathogenesis and current management. DEVELOPMENT GTS is a disorder characterized by a spectrum of both motor and sonic tics, and a spectrum of behavioral disorders. There is not a biological marker tha...

We introduce a new game-theoretic semantics (GTS) for the modal mu-calculus. Our so-called bounded GTS replaces parity games with alternative evaluation where only finite paths arise; infinite are not needed even when considered transition system is infinite. The novel offer approaches to various constructions in framework of While our main focus introducing GTS, we also consider some applicati...

One approach for the identification of therapeutic agents for Alzheimer's disease has focused on the research of alpha7 nAChR-selective agonists such as the partial agonists 3-(4-hydroxy,2-methoxybenzylidene)anabaseine (4OH-GTS-21) and, more recently, 2-[2-(4-bromophenyl)-2-oxoethyl]-1-methyl pyridinium (S 24795). An alternative approach for targeting alpha7 nAChR has been the development of po...

We have shown previously that a highly conserved Tyr in the nicotinic acetylcholine receptor (nAChR) ligand-binding domain (LBD) (alpha7 Tyr188 or alpha4 Tyr195) differentially regulates the activity of acetylcholine (ACh) and the alpha7-selective agonist 3-(4-hydroxy,2-methoxybenzylidene)anabaseine (4OH-GTS-21) in alpha4beta2 and alpha7 nAChR. In this study, we mutated two highly conserved LBD...

CONTEXT Gilles de la Tourette syndrome (GTS) is a hyperkinetic movement disorder with heterogeneous phenotypic expression ranging from simple motor and vocal tics to more complex tics associated with psychiatric comorbidities. The heterogeneity of clinical phenotypes may relate to the dysfunction of distinct frontal cortex-basal ganglia circuits. OBJECTIVES To assess the hypothesis that simpl...

brassica chinensis l. is a popular vegetable, especially in asian dishes. for plant growing withinorganic fertilizer, cadmium (cd) has been one of the highest metal and health-risk factors included. thisresearch aimed to assess the bioaccumulation of cd by the plant and its genetic changes. the plant was grownin the soil supplemented by cd at 0, 15, 30, 60 and 120 mg/kg. the accumulations in th...