BACKGROUND This study aims to investigate anti-inflammatory effect of ethanolic extract of Myagropsis myagroides (EMM) in the lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages and the phorbol 12-myristate 13-acetate (PMA)-induced ear edema in mice, and to clarify its underlying molecular mechanisms. METHODS The levels of nitric oxide (NO), prostaglandin E2 (PGE2), and pro-inflammatory...

Aberrant activation of extracellular signal‑regulated kinase 1/2 (ERK1/2) by phosphorylation modification can trigger tumor cell development in glioma. S‑nitrosylation, which refers to the covalent addition of a nitric oxide (NO) group to a cysteine (Cys) thiol, is an important post‑translational modification that occurs on numerous cancer‑associated proteins. Protein S‑nitrosylation can increa...

We present a family of conformal field theories (or candidates for CFTs) that is build on extremal partition functions. Spectra of these theories can be decomposed into the irreducible representations of the Fischer-Griess Monster sporadic group. Interesting periodicities in the coefficients of extremal partition functions are observed and interpreted as a possible extension of Monster moonshin...

testosterone level was determined in six different populations of iran using saliva steroid assay. significant difference was observed in morning and afternoon testosterone level of the same individual (p>0.00l) significant difference was also noticed among different regions studied (p>0.00 1). comparisons between alcoholics and nonalcoholic as well as smokers and nonsmokers showed significant ...

In forensic ballistics, gunshot residue (GSR) particles can be detected using screening or presumptive tests which are mainly focused on the chromophoric reaction. Most serve as an initial indication for a investigator at crime scene before instrumental analysis definitive identification. The methods known to convenient, have fast analysis, and minimal preparation. GSR well-known method of dete...

AbstractIn the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µM) in presence of D-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. Cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by MTT assay, the modified Griess method and Fura-2 respectively. 25 and 100...

Objective(s) The fractions of Candida albicans have been used as an immunomodulator. The present work assessed the effect of different fractions of C. albicans on nitric oxide (NO) production by mice peritoneal macrophages. Materials and Methods Cell wall and cytoplasmic fractions of C. albicans ATCC 10321 strain were extracted. Mice peritoneal macrophages were purified and cultured. Differen...