BACKGROUND Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies evaluating the effects of cigarette smoke on these events are lacking. MATERIAL AND METHODS We used gingival fibroblasts cultured within free-floating and restrained collagen gels...

BACKGROUND Airway granulation tissue and scar formation pose a challenge because of the high incidence of recurrence after treatment. As an emerging treatment modality, topical application of mitomycin C has potential value in delaying the recurrence of airway obstruction. Several animal and clinical studies have already proven its feasibility and efficacy. However, the ideal dosage has still n...

procera produce milky white latex that causes inflammation of the skin and mucous membranes. Prostaglandins are one of the mediators released in an inflammatory response following induction of cyclooxygenase (COX). In the present study, we have evaluated the role of prostaglandins in inflammatory response elicited by the latex of C. procera . Methods: Aqueous extract of dried latex of C. procer...

BACKGROUND This study was performed to evaluate the results of negative pressure wound therapy (NPWT) in patients with open wounds in the foot and ankle region. MATERIALS AND METHODS Using a NPWT device, 16 patients were prospectively treated for soft tissue injuries around the foot and ankle. Mean patient age was 32.8 years (range, 3-67 years). All patients had suffered an acute trauma, due ...

Among the odontogenic cysts, there are radicular cysts or also called periapical most common cyst. They develop at apex of a tooth with pulp necrosis, which may be consequence dental caries trauma. they asymptomatic, grow slowly, and discovered on routine radiographs. With proliferation ERM its activation, is an increase in osmotic pressure, causing cyst to expand, normally this not activated, ...

OBJECTIVE To investigate whether airway granulation, a common occurrence during laryngotracheal reconstructive surgery and a common cause of delays in definitive treatment and treatment failure, is associated with a microbial etiology. DESIGN Prospective case-control study. SETTING Tertiary referral airway reconstruction unit. PATIENTS Patients who had an airway stent as part of their tre...

Augmentation of viability random pattern flaps has long been an issue in plastic surgery. Up to date no agents were clinically introduced. Atorvastatins are used for lipid lowering. They also effective on flap survival with their angiogenic, anti-inflammatory, antioxidant effects systeic administration. In this study, Atorvastatin is topically alleviation Mc Farlane rats. Wibstar albino type 20...