Cells of the basal, spinous, and granular layers of the mammalian epidermis represent morphological stages in the differentiation of keratinocytes to form the outer cornified layer of the skin. In the newborn rat, concomitant with the transition of granular into cornified cells, there is a conversion of histidine-rich protein I (HRP,), localized in keratinocytes of the epidermal granular layer,...

T~Sik, 1.: Less Common Cell Types in the Tracheal Epithelium of Reptiles. Acta vet. Brno, 61,1992: 17-22. Tracheal epithelium of representatives of21 reptile species of 10 families was found to consist of several cell types. The first in the order of frequency were ciliated, goblet and granular cells followed by their considerably fewer precursors basal cells, and rare intermediary cells. Plasm...

Gastrointestinal granular cell tumors (GCTs), usually benign, soft-tissue tumors, are thought to arise from Schwann cells that may occur at many sites. Only 5-7% of these lesions are detected in the gastrointestinal tract. Histologically, it is composed of sheets or nests of plump round or polygonal cells having abundant slightly amphophilic granular cytoplasm with centrally located uniform pyk...

Silos are structures that are used for storing different types of granular material. Dynamic behavior of silos under seismic loads is very complex. In this paper seismic behavior of steel silos with different height to diameter ratios is investigated by considering granular material-structure interaction using ABAQUS finite element package. Silo wall is modeled by shell elements and its behavio...

background: since embryonic stem (es) cells have the dual ability to proliferate indefinitely and differentiate into multiple tissue types, es cells could potentially provide an unlimited cell supply for human transplantation. objective: in order to study the differentiation of mouse embryonic stem (mes) cells, they were cultured in suspension by using es media without leukemia inhibitory facto...

Morphological, immunologic, and functional properties of peripheral blood cells from two patients with chronic proliferations of granular lymphocytes are described. Cells from both patients showed a heterogeneous pattern from both a morphological and immunologic standpoint, indicating a polyclonal, rather than a monoclonal, expansion of these cells. In fact, both large and small-to-medium-sized...

A 33 year-old man, a renal transplant recipient, developed an aggressive T-cell large granular lymphocytic leukemia (LGL) that presented as a soft-tissue lesion, mimicking an abscess. The tumor cells showed cytological features of large granular lymphocytes, immunophenotypically characterized as mature T-cells expressing CD2, CD5, CD4, CD56, and TIA-1. About 80% of tumor cells were positive for...

It is presented the case of an old female with a solitary tumor at the level of the thorax. The specimen was processed using the routine histological technique and slides were stained with conventional morphologic, histochemical and immunohistochemical methods. On Hematoxylin-Eosin stained slides were noticed large cells with acidophilic cytoplasm, with granular pattern. S100 protein was intens...

Renin release from juxtaglomerular granular cells is considered the rate-limiting step in activation of the renin-angiotensin system that helps to maintain body salt and water balance. Available assays to measure renin release are complex, indirect, and work with significant internal errors. To directly visualize and study the dynamics of both the release and tissue activity of renin, we isolat...