The case is presented of a patient with mild rheumatoid arthritis who developed an enlarged painful tissue mass in the left lower leg. Although the history, clinical, and imaging appearances suggested that it was a soft tissue sarcoma, a biopsy specimen showed histological features consistent with either a rheumatoid nodule or subcutaneous granuloma annulare.

We describe the case of a patient with multiple paraneoplastic syndromes, six in total, associated with a non-small-cell cancer of the lung. In this single patient we found hypertrophic pulmonary osteoarthropathy, hyperkeratosis of palms and soles, erythema annulare centrifugum, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and ectopic andrenocorticotrophic hormone (ACTH)...

Background: Granuloma annulare is a difficult disease to treat and can lead anxiety frustration for both patients providers. The pathogenesis of granuloma unknown, resulting in few thoroughly studied or consistently effective treatments.
 Objective: 1) To discuss whether treatment with apremilast could improvement resolution generalized annulare. 2) explore the possible mechanism treating ...

Sir, Granuloma annulare (GA), a granulomatous disease of unknown aetiology, is characterized by small papules that are often fused into annular arrangements. Several variants are known: localized GA, generalized GA, subcutaneous GA, perforating GA and arcuate dermal erythema. Localized GA is the most common of the subtypes; 9 – 15% are afflicted with the generalized variant. The other subtypes ...

Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness.

BACKGROUND Ultraviolet radiation has been used for curative purposes in dermatologic conditions, especially in the last 30 years. OBJECTIVES We analyzed the efficacy of monochromatic excimer light in psoriasis, palmoplantar pustulosis, vitiligo, mycosis fungoides and alopecia areata, and to examine potential new indications. METHODS Two hundred seventy-nine patients with common and persiste...

PURPOSE To report a case of uveitis associated with granuloma annulare (GA). GA is a benign, usually self-limited dermatosis of unknown origin, causing necrobiotic dermal and subcutaneous papules. So far, ocular involvement has not been reported in GA. METHODS We describe a case of uveitis with GA. Ocular examination findings were consistent with uveitis. Histopathologic studies on lower extr...