Hypogonadism, whether caused by the failure of gonadal development or function, frequently results in bone loss. In a research article in the April 21, 2006 issue of Cell, Sun et al. investigated the role of follicle-stimulating hormone (FSH) in the bone loss that is characteristic of hypogonadal mice. They report that female mice lacking either FSHβ or its receptor (FSHR) are resistant to bone...

The large macroand microscopic variability in kidney morphology among fish makes it difficult to build a “universal” understanding on its function and structure [1]. Species-specific studies are thus needed. Thus, morphological study of brown trout trunk kidney was performed, considering potential seasonal and gender effects. Three-year-old specimens of both genders were collected at four stage...

The leukemia is considered to be one of the most frequent tumors in childhood. The first line of its treatment is 6-mercaptopurine (6-MP). There are many recorded cytotoxic effects for 6-mercaptopurine on tissues such as liver, pancreas and bone marrow. Nowadays the needs for administration of cytotoxic drugs are increased as the incidence of malignancies increases. So we have to search for a s...

The main focus of the study was to assess effect lipid levels on reproduction female orange mud crab, Scylla olivacea. Four isonitrogenous feed (~420 g/kg) were formulated with different percentages: T 1 = 60 g / kg , id="M2"> 2<...

intervene therapeutically with children exposed to disasters affecting the adults in their world. New prospects for luteinising hormone releasing hormone as a contraceptive and therapeutic agent Gonadal function is controlled by luteinising hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Since the release of these hormones depends on secretion of hypothalamic lutei...

Gender issues in epilepsy–—The science of why it is special Epilepsy is recognized as one of the most common serious neurological disorders in the world. During the last years, one has become increasingly aware that epilepsy has different implications for life and well-being in men and women. People with epilepsy experience several gender-related physical and social problems and the last decade...

Germinal damage is an almost universal accompaniment of cancer treatment as the result of bystander damage to the testis from cytotoxic drugs and/or irradiation. Cancer treatment for the most common cancers of the reproductive age group in men has improved such that most are now treated with curative intent, and many others are treated with likelihood of prolonged survival, so that the preserva...

Mating has been shown to have effects on ovulation in a number of species which ovulate spontaneously, such as rats (Aron, Asch & Asch, 1961; Aron, Asch & Ross, 1966; Zarrow & Clark, 1968) and sheep (Parsons, Hunter & Rayner, 1967; Van der Westhuysen, Van Niekerk & Hunter, 1970). In the sow, the results obtained by Pitkjanen (1955) and Lebedev (1957) suggest that mating hastens ovulations and s...

Two methods were used to estimate the reproductive output of female Pacific oysters reared in Normandy: histology with image analysis and ELISA (Enzyme-Linked ImmunoSorbent Assay) which allowed the quantification of egg protein. Condition indices, gonad area and gametogenetic stages of the oysters were determined in the entire population (males and females) between May and October 2005. All inv...

Abbreviations: DTT-dithiothreitol IAA-iodoacetamide LC-MS/MS-liquid chromatography (nano HPLC) and mass spectrometry SDS-sodium dodecyl sulphate T he human tear has the primary function to lubricate the cornea and to be the first-line protective surface against pathogens. Due to difficulties with their collection, tears are rarely utilized in clinical medicine. Nevertheless, these exocrine secr...