Background: Cervical cancer is the second most common female cancer worldwide. Inhibitors of apoptosis proteins (IAPs) block apoptosis; therefore, therapeutic strategies targeting IAPs have attracted the interest of researchers in recent years. Apollon, a member of IAPs, inhibits apoptosis and cell death. RNA interference is a pathway in which small interfering RNA (siRNA) or shRNA (short hairp...

Objective: This study compared the effect of abdominal exercise versus ultrasound cavitation on coronary risk profile in obese women by 6 week program. Material and Methods: Forty obese women with abdominal obesity, their age ranged from (30-40) years, their BMI (30-35kg/m), WHR ranged between (0.81 to 1.0) selected from Ibrahim nada hospital, and divided into two equal groups. Group (A): Recei...

Ultrasound and microbubble-based therapies utilize cavitation to generate bioeffects, yet cavitation dynamics during individual pulses and across consecutive pulses remain poorly understood under physiologically relevant flow conditions. SonoVue(®) microbubbles were made to flow (fluid velocity: 10-40 mm/s) through a vessel in a tissue-mimicking material and were exposed to ultrasound [frequenc...

Estradiol valerate (Exogenous estrogen) is a synthetic ester and is also a female estrogen hormone. There arestudies showing that estradiol may have anticancer effects. This study was performed to reveal the effects ofexogenous estrogens on the viability of cervical cancer cells in cell culture. We used Hela cells as our cell linein this study. Hela cells were exposed to 0.0001, 0.001, 0.01, 0....

Introduction Ultrasound is widely applied in the clinical field today, such as ultrasound contrast agent imaging, High Intensity Focused Ultrasound (HIFU), Extracorporeal Lithotripsy, sonodynamic therapy. Some of these have a close relation to the dynamic behavior of micro bubbles and that of a bubble cloud. In an ultrasound imaging, micro bubbles are used as contrast agents. Extracorporeal Foc...

Background: This work evaluated the efficiency of common ultrasound stimulation (U.S.S) types on bacterial growth in vitro using clinically relevant conditions.Objective: To estimate different frequencies ultrasound bactericidal ability on bacteria in bacteria of Pseudomonas Aeruginosa. Methods: Six types of U.S.S (continuous wave, 7w/cm2, 20 KHz; continuous wave, 35w/0.8L, 40 KHz; continuous ...

Introduction: Stroke causes death and disability in patients throughout the world. At present, the only FDA- approved drug for ischemic stroke is recombinant tissue plasminogen activator (rt- PA). Unfortunately, rtPA can cause intracerebral hemorrhage and must use within limited time window (within 3-4.5 hour after onset of stroke). Ultrasound with rtPA loaded liposomes (rtPA_L...

The impact of radiation-induced bystander effect (RIBE) is still not well understood in radiotherapy. RIBEs are biological effects expressed by nonirradiated cells near or far from the irradiated cells. Most radiological studies on cancer have been based biochemical characterization. However, biophysical investigation with label-free techniques to analyze and compare direct irradiation RIBE has...

The ultrasonic propulsion of rod-shaped nanomotors inside living HeLa cells is demonstrated. These nanomotors (gold rods about 300 nm in diameter and about 3 mm long) attach strongly to the external surface of the cells, and are readily internalized by incubation with the cells for periods longer than 24 h. Once inside the cells, the nanorod motors can be activated by resonant ultrasound operat...

This review is concerned with (1) certain physiological and structural changes produced in tissues of the central nervous system caused by high level ultrasound and (2) investigations into the physical mechanisms underlying these changes. The cell bodies of neurons in the central nervous system are particularly susceptible to change by ultrasound. The effect of irradiation is immediately eviden...