BACKGROUND Thyroid antibody testing is not routinely available in developing countries, and few studies have measured thyroid antibodies in Africans. The significance of thyroid autoimmunity in an African setting is thus unclear. AIM To determine the prevalence of thyroid antibodies in patients attending a Nigerian teaching hospital. DESIGN Prospective survey. METHODS We measured antibodi...

During the present century, a great deal of the earlier work has been confirmed and still further progress made in our knowledge of the problem. The application of iddine therapy in the prophylaxi s and treatment of goitre was commenced. In America in 1910 Marine found that goitre in brook trout could be prevented.by the administration of Iodine, subsequently he found the same, result to apply ...

IN 1932, Cecil Joll, in his book "Diseases of the Thyroid Gland" emphasised that "although respiratory symptoms due to tracheal compression and alteration of voice were common", dysphagia was a "decidedly rare feature of simple goitre". Since then there has been little documentation on the subject. The following is an account of the symptoms found in a series of patients undergoing surgery for ...

A case of histiocytosis X involving the thyroid and hypothalamus is reported. A 16 year old female presented with amenorrhoea and diabetes insipidus. She subsequently developed a painful goitre with biochemical hypothyroidism, and stridor. The stridor and goitre responded to cyclophosphamide. Previous publications on the use of cytotoxics in histiocytosis X involving the thyroid are reviewed. W...

The junior writer first broached the subject of intravenous injections of sodium iodide for the treatment of goitre with a view to testing:? (1) Whether sodium iodide orally was beneficial in cases of goitre. (2) Whether iodine is essential for the good functioning of the thyroid gland. (3) Whether the oral administration of sodium iodide could prevent the disease. He suggested that it might be...

Iodine goitre and hypothyroidism in 5 newborn infants in an intensive care unit were induced by cutaneous absorption of iodine, after numerous skin applications of iodine alcohol. The infant's skin permeability allows severe iodine overloading of the thyroid, resulting in goitre and hypothyroidism. Ioduria should always be sought in a newborn infant showing hypothyroidism. Iodine should not be ...