A retrospective study of all patients with goitre seen from 1988 to 1992 inclusive at the Muhimbili Medical Centre, Dar es Salaam was made to determine the frequency of malignancy in patients with solitary non-toxic thyroid nodule (STN) and in those with multinodular goitre (MNG). There were 60 cases of STN and 178 with MNG. Nodular goitre was found to be predominantly a disease of females with...

A person suffering from goitre, who has no dyspnoea or only a very moderate degree of it, may have a sudden and urgent attack, which may be very quickly fatal. There are various theories to account for this, but none of them seem very satisfactory. If hemorrhage has taken place into the goitre, or from the goitre into the tissues around?a condition found in a few of the cases,?we can readily un...

Our aim is to shed light on the relationships between research, knowledge, and policy in case of goitre use iodine as a preventive measure against it Norway from 1850s onward. Goitre was previously widespread certain areas Norway, but disappeared around 1950. After many decades silence about iodine, an expert report 2016 argued that action should be taken prevent deficiency. Already 1927, inter...

Background: Enlargement of thyroid gland is the most common manifestation disease. Most patients come from endemic zones. This study was designed to various aspects clinicopathological presentations multinodular goitre and their optimal surgical management. Methods: a prospective observational 50 cases with an adequate follow up look for epidemiological parameters such as clinical presentation,...

609 samples of drinking water collected from scattered sources from the eight districts of Kandy, Matale, Kalutara, Anuradhapura, Polonnaruwa, Colombo,. Puttalam and Gampaha were analysed for iodide content using the Orion electrode method. The median iodide content of all districts except Gampaha were above 10 u g / 1 , with Anuradhapura showing the highest content. Districts with low prevalen...

Ahigher frequency of skewed X chromosome inactivation (XCI) is found in patients with autoimmune thyroid disease (AITD) than in controls. Although goitre is often present in AITD, a recent study failed to show an association between XCI and clinically overt nontoxic goitre. However, the etiology of overt goitre is complex, and the mechanisms influencing thyroid volume may involve fewer factors ...