نتایج جستجو برای: glucose 6

تعداد نتایج: 1108696  

2014
Shaji Chacko Siddhesh Prabhavalkar

www.ums.ac.uk FDG will be metabolised and replaced by unlabelled glucose. If a malignant cell is present, the continued FDG uptake between scans results in higher intensity of retained FDG at 4 hours. Inflammatory cells, which retain normal glucose-6-phosphatase activity, will have decreased signal. In our experience, a rise in SUVmean of 30% correlates with malignant disease, with no increase ...

2015
Malay B. Mukherjee Roshan B. Colah Snehal Martin Kanjaksha Ghosh

It is believed that the tribal people, who constitute 8.6 per cent of the total population (2011 census of India), are the original inhabitants of India. Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is an X-linked genetic defect, affecting around 400 million people worldwide and is characterized by considerable biochemical and molecular heterogeneity. Deficiency of this enzyme is highly ...

Journal: :Haematologica 2005
Naif S Karadsheh Linda Moses Said I Ismail Joseph M Devaney Eric Hoffman

Molecular screening for glucose-6-phosphate (G6PD) mutations in two Jordanian populations revealed six different mutations and higher incidences of G6PD deficiency and G6PD A- (376A-->G + 202G-->A) mutation in Jordan Valley than in the Amman area. These observations may be explained by historically higher rates of malaria and African ancestral origins, respectively.

Journal: :The Biochemical journal 1988
I D Waddell A Burchell

Microsomal fractions isolated from pancreatic islet cells were shown to contain high specific glucose-6-phosphatase activity. The islet-cell glucose-6-phosphatase enzyme has the same Mr (36,500), similar immunological properties and kinetic characteristics to the hepatic microsomal glucose-6-phosphatase enzyme.

Journal: :Journal of vector borne diseases 2008
Viroj Wiwanitkit

High prevalence of malaria in Southeast Asia including Thailand is believed to be a major public health problem to the population in this area since time immemorial. Adaptation of the population in this area following the principle of natural selection coupled with genetic disorders can be expected. Some good examples for natural selection of malaria are the co-existence of high prevalence of t...

Journal: :Genetics 1986
W F Eanes J Hey

From 1981 to 1983, 15,097 X-chromosomes were genetically extracted from a number of North American populations of D. melanogaster and were electrophoretically screened for rare mobility and activity variants of glucose-6-phosphate dehydrogenase (G6PD). Overall, 13 rare variants were recovered for a frequency of about 10(-3). Eleven variants affect electrophoretic mobility and are apparently str...

2011
Sule Menziletoglu Yildiz Sedefgul Yuzbasioglu Ariyurek Murat Tahiroglu Kiymet Aksoy

INTRODUCTION Nucleotide 1311 polymorphism at exon 11 of the glucose-6-phosphate dehydrogenase (G6PD) gene is fairly common in various populations worldwide, especially among Mediterranean populations. In this study, 1311 polymorphism in G6PD-deficient cases was identified by microarray technique. MATERIAL AND METHODS Four hundred and fifty clinically healthy subjects were screened and 32 case...

Journal: :Seminars in perinatology 1992
M Kaplan C Hammerman R Kvit B Rudensky A Abramov

Eight hundred and six newborn infants at high risk for glucose-6-phosphate dehydrogenase (G-6-PD) deficiency were screened; 30.2% of the boys and 10.4% of the girls had severe G-6-PD deficiency. Surprisingly, 14% of the enzyme deficient girls had a father from a low risk ethnic group. Girls of high risk mothers should be screened for G-6-PD deficiency regardless of paternal origin.

Journal: :Journal of bacteriology 1967
W de Vries A H Stouthamer

Cell-free extracts of 17 strains of Bifidobacterium bifidum (Lactobacillus bifidus) were examined for the presence of aldolase, glucose-6-phosphate dehydrogenase, and fructose-6-phosphate phosphoketolase. All strains turned out to lack aldolase, an enzyme unique to glycolysis, and glucose-6-phosphate dehydrogenase, characteristic of the hexosemonophosphate pathway. In all strains, fructose-6-ph...

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