نتایج جستجو برای: global brain ischemia
تعداد نتایج: 974514 فیلتر نتایج به سال:
OBJECTIVES The influence of 5-hydroxyadamantane-2-on was studied on the rats' brain blood flow and on morphological state of brain tissue under the condition of brain ischemia. The interaction of the substance with NMDA receptors was also studied. METHODS Study has been implemented using the methods of local blood flow registration by laser flowmeter, [(3)H]-MK-801binding, and morphological e...
Abstract Background: Stroke is the second leading cause of death in the world and has irreversible consequences. Cerebral ischemia/reperfusion (I/R) through production of oxidants and inflammatory markers causes apoptosis of brain neurons. On the other hand, in various studies, the antioxidant and anti-inflammatory effects of the Malva neglecta have been proven. Therefore, in this study, we inv...
BACKGROUND Global cerebral ischemia following cardiac arrest is associated with increased cerebral vasoconstriction and decreased cerebral blood flow, contributing to delayed neuronal cell death and neurological detriments in affected patients. We hypothesize that upregulation of contractile ETB and 5-HT1B receptors, previously demonstrated in cerebral arteries after experimental global ischemi...
329 stated that "The model was soon found to be unreliable, perhaps due to failure to document a lack of brain blood flow during the ischemic period and to nonstandardized postischemic supportive care, aspects of peri-ischemic handling that were not appreciated at this time." In fact, the model itself was never unreliable, as the results in our first report showed.' Indeed, in developing the mo...
Background: Q10 coenzyme is a potent antioxidant in the mitochondrial membrane. Releasing the oxygen free radicals occurs in the cerebral ischemia. Using Q10 coenzyme causes strength against oxidative after injury of cerebral ischemia during reperfusion. Also CoQ10 plays an important anti-apoptotic role to reduce Caspase 3 as a key enzyme neuroprotective in apoptosis. According to the sensitive...
Objective(s): Cerebral ischemia/reperfusion causes complex pathological mechanisms that lead to brain tissue damage. Usnic acid is a lichen secondary metabolite that has many different biological properties including anti-inflammatory and anti-oxidant activities. Therefore, the objective of the current study was to investigate the neuroprotective effects of usnic acid ...
Background: Stroke is the third leading cause of invalidism and death in industrialized countries. There are conflicting reports about the effects of Angiotensin II on ischemia-reperfusion brain injuries and most data have come from chronic hypertensive rats. In this study, hypotensive and non-hypotensive doses of candesartan were used to investigate the effects of angiotensin II AT1 receptor b...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید