The distribution of peptide-containing nervous systems in the rat glandular stomach was studied immunohistochemically by use of the cryostat sections and whole mount preparations. A variety of peptide-containing nerve fibers made a dense network in the mucosa, submucosa, smooth muscle layers and intramural ganglia. Distribution density was the highest for nerve fibers containing vasoactive inte...

interest in hydroxy - carboxylic acid 2 (hca2) receptor has been raised since it is the target of antidyslipidemic drug nicotinic acid. the present study aimed to evaluate the presence of mrna of this receptor in different organs of laboratory rat. twenty two different organs of rats including mesenteric fat, epididymis (head, body and tail), testis, ovary, xiphoid process, liver, adrenal gland...

A rat immobilized for 24 hours will develop ulcerations in the glandular area of the stomach."'3 Although these ulcers or erosions have been attributed to stress, the mechanism that causes them is unknown.! Both vagotomy and anticholinergic drugs reduce the incidence of these ulcers, suggesting the role of acid in their production.2"'3 Studies to date, however, have failed to show consistently ...

The term Equine Gastric Ulcer Syndrome (EGUS) was first used in 1999 to describe gastric ulceration in the horse. However, as discussed by Merritt, the terminology is commonly misused. The committee reinforces the importance of distinguishing between diseases of the squamous and glandular mucosa because, as discussed in this statement, important differences exist between the two. In human medic...

Oxazepam and related benzodiazepines are used in the treatment of anxiety. Carcinogenicity studies of oxazepam were performed with the F344 rat because of marked differences in tumor responses observed in NTP studies with B6C3F1 and Swiss-Webster mice compared to the results of Sprague-Dawley rat studies submitted to the FDA by a manufacturer to support registration of the drug. Groups of 50 ma...

Extract of gazyagi has protective effect against ethanol-induced gastric ulcer and it decreases microscopical ulcer index in rat. At the last some years, treatment of peptic ulcer by medicinal herbs have been were very successful. Gazayagi (Falcaria vulgaris) is a member of Umbelliferae family. In the folk medicines of the west of country, this herb is used for healing of skin ulcer and peptic ...