This study was designed to investigate the hypoglycaemic and anti-oxidant effects of Zingiber officinale on experimentally induced diabetes mellitus using alloxan and insulin resistance. Aqueous extracts of raw ginger was administered orally at a chosen dose of 500mg/ml for a period of 4 weeks to alloxan-induced diabetic and insulin resistant diabetic rats. The experimental rats exhibited hyper...

Background: Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice and has anti-oxidant and cell-protective effects in animals and humans body. Objective: The aim of this study was to investigate the influence of Ginger rhizome toxicity of Gentamicin on sperm parameters in male rats. Methods: Forty Wistar male rat (n=40) were allocated into fo...

The Japanese traditional medicine daikenchuto (TU-100) has anti-inflammatory activities, but the mechanisms remain incompletely understood. TU-100 includes ginger, ginseng, and Japanese pepper, each component possessing bioactive properties. The effects of TU-100 and individual components were investigated in a model of intestinal T lymphocyte activation using anti-CD3 antibody. To determine co...

Zingiber officinale Roscoe, commonly known as ginger, is a traditional herb used to treat various disorders. In this study, we evaluated potential pharmacological effects of ethanolic extracts of Z. Officinale with respect to central nervous system (CNS) activity in mice. Role of ethanolic extract of ginger on CNS activity in mice was studied using models of elevated plus maze test, barbiturate...

BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. The pathogenesis of this disease is closely associated with obesity and insulin resistance. Ginger can have hypolipidemic and antioxidant effects, and act as an insulinsensitizer. OBJECTIVES The aim of this study was to evaluate the effects of ginger supplementation in NAFLD managem...

Ginger effects on blood glucose, lipids, oxidative stress and early stages of atherogenesis in diabetic cholesterol fed rats were investigated in the present study. Sprague-Dawley male rats were divided into three main groups of eight animals each. The animals of the first group were fed on a commercial pellet diet and served as control. Diabetes was induced in both second and third group of an...

The ameliorating potentials of ginger incorporated feed (10%) on the relative organ weights of Streptozotocin (STZ) induced diabetic rats was investigated. The experiment lasted for three weeks. Results show that administration of 10% ginger feed to the diabetic rats of group 3, resulted in a 29.81% decrease in their resulting hyperglycemia with a corresponding amelioration of elevated urinary ...

BACKGROUND Trichomoniasis is the most common sexually transmitted protozoan diseases in the worldwide. Metronidazole is the choice drug for trichomoniasis treatment, however, metronidazole resistant Trichomonas vaginalis (T.vaginalis) has been reported. Natural products are the source of most new drugs, and Zingiber officinale (Ginger) is widely used ingredient in the traditional medicine. OB...

Previous research showed that exposure to ginger root, Zingiber officinale Roscoe, oil increased the mating success of mass-reared, sterile males of the Mediterranean fruit ßy, Ceratitis capitata (Wiedemann). This work, however, involved the exposure of small groups of males (n 25) in small containers (volume 400 ml). Several sterile male release programs use plastic adult rearing containers (s...

The antibacterial activity of ethanol extract of Zingiber officinale Roscoe (ginger) and its combination with different salts like CuSO4, ZnSO4 and MnCl2 was investigated. Both Gram positive and Gram negative bacteria were tested by agar diffusion method. The results showed that ethanol extract of Zingiber officinale gave the maximum zone of inhibition at 50mg/ml concentrations against Escheric...