objective: maternal type and amounts of dietary fatty acids affect on reproductive process in the mice. the present study investigated the effects of maternal supplementation with different amounts of omega-6 or omega-9 during pregnancy on the number of offspring, sex-ratio and duration of gestation. materials and methods: eight-week-old female c57bl/6 mice were randomly assigned into four diet...

BACKGROUND Previous studies of preterm-born children (<37 weeks' gestation) have demonstrated decrements in lung function, exercise capacity, and increased respiratory symptoms compared to their term-born peers. However, it is unclear if these children have decreased levels of physical activity (PA) and increased sedentary behavior as a consequence of this increased respiratory morbidity. We th...

Three experiments were conducted to determine gestational age in the ewe and doe by measuring placentomes with a B-mode ultrasonograph and a 5 MHz transducer. Transrectal measurements were obtained by placing the female over a bale of hay. In Experiment 1, ewes (n = 12) and does (n = 15) were examined by transrectal ultrasonography every week from breeding to parturition to determine the growth...

term "large granules." It is of some interest that these granules behave in many ways like the granules of the adrenal medulla which contain the pressor amines. By differential centrifugation it has been shown that the granules with the greatest density contain the largest amount of histamine, and also, that the intravenous injection of a preparation of these granules has less vasodepressor act...

BACKGROUND While the reduction in infants' prone sleeping has led to a temporal decline in Sudden Infant Death Syndrome (SIDS), some aspects of this trend remain unexplained. We assessed whether changes in the gestational age distribution of births also contributed to the temporal reduction in SIDS. METHODS SIDS patterns among singleton and twin births in the United States were analysed in 19...

The impact of very immature infants on neonatal services was examined within the United Kingdom. The Trent Health Region was used as a geographically defined population. Data were obtained on all infants weighing less than 1501 g at birth and all infants born before 32 weeks gestation between 1991-93. Information relating to length of stay, duration of ventilation, and survival was documented. ...

Background: Most severe and fatal cases of pertussis occur in infants younger than eight weeks of age, before initiation of the primary pertussis vaccine series. To help protect infants from pertussis during this vulnerable period, women are recommended to receive Tdap vaccine at the start of the third trimester of each pregnancy to optimize transplacental transfer of antibodies to the fetus. T...

Gestational diabetes mellitus is a major complication of human pregnancy. The oral clearance (CL) of glyburide, an oral antidiabetic drug, increases 2-fold in pregnant women during late gestation versus nonpregnant controls. In this study, we examined gestational age–dependent changes in maternal-fetal pharmacokinetics (PK) of glyburide and metabolites in a pregnant mouse model. Nonpregnant and...

The chimpanzee fetuses used in our study showed a significant agerelated change in brain volume over the course of the study period (Figure 1B,C). The volume of the chimpanzee brain increased nonlinearly from 14 to 34 weeks of gestation (F = 634.28; cubic effect, p < 0.0001) (Figure 1C). The brain volume of the chimpanzee was only half that of the human fetus at 16 weeks of gestation (15.8 cm3;...