INTRODUCTION Ghrelin is a hormone which has effects on the secretion of growth hormone, gastrointestinal system, cardiovascular system, cell proliferation and reproductive system. The present study we focused on the relation between ghrelin and GHS-R1a gene expression and the regulation of their expression in the testes of diabetic rats. MATERIAL AND METHODS 40 male Wistar albino rats were di...

The early development of chick embryo gonads was studied by light and transmission electron microscopy and by cytochemical detection of glycogen in primordial germ cells (PGC's). The sequential events are presented from day 2 to day 5 (stages 14 to 27), together with the ultrastructural characteristics of the various cell populations. This study attempts to contribute data on the controversial ...

Background Mesenchymal stem cells (MSCs), have been suggested as a potential choice for treatment of male infertility. Yet, the effects of MSCs on regeneration of germinal epithelium of seminiferous tubules and recovery of spermatogenesis have remained controversial. In this research, we have evaluated and compared the fate of autologous bone marrow (BM)-MSCs during three different periods of t...

The recently identified CXCL16 has dual functions as a transmembrane adhesion molecule and a soluble chemokine. In this study we found that CXCL16 mRNA and protein were expressed constitutively on the follicle-associated epithelium covering Peyer's patches (PPs), isolated lymphoid follicles, and cecal patches, but minimally on the villous epithelium in the murine gastrointestinal tract. The CXC...

The epithelial cell adhesion molecule (Ep-CAM) exhibited an ovarian cancer:normal human ovarian surface epithelium ratio of 444. For validation studies, real-time quantitative PCR analysis and immunohistochemistry were performed in normal and malignant ovarian epithelial cell lines and tissues. To evaluate the potential of the Ep-CAM autoantibody as a tumor marker, we examined the amount of Ep-...

background: cryopreservation and in vitro maturation (ivm) of oocyte is becoming an important technique in infertility treatment and fertility preservation. also it has been proposed to establish a genetic resource bank for endangered or commercially important animal species. objective: the aim of this study was to evaluate viability, maturation and fertilization rate of mouse immature oocytes ...

Background: Toxic effect of alcohol and nicotine on the other organs of body has been proven to some extent. Effects of oral alcohol and subcutaneous nicotine co-administration on spermatogenesis in rat are the aim of this study. Materials and Methods: Thirty healthy Spauge-Dawley male rats (average weight 160-210 g) were randomly divided to 3 groups (n=10). The animals in the first group recei...

The author investigated histopathology of 615 consecutive duodenal specimens in our pathology laboratory. Computer search of the duodenal lesions was performed. Review of histological slides was done, when appropriate. The duodenal specimens were composed of 567 benign lesions and 48 malignant lesions. The 567 benign lesions were composed of chronic non-specific duodenitis in 334 cases (60.0%),...

germinal matrix-intraventricular hemorrhage (ivh) is the most common variety of neonatal intracranial hemorrhage and is characteristics of the premature infant. the importance of the lesion relates not only to its high incidence but to their attendant complications (ic: hydrocephalus). brain sonography is the procedure of choice in diagnosis of germinal matrix- intraventricular hemorrhage and h...