نتایج جستجو برای: germ cell neoplasm
تعداد نتایج: 1805449 فیلتر نتایج به سال:
Testicular cancer has become a model for a curable neoplasm. The results of the treatment of disseminated germ-cell tumors have dramatically improved by utilization of platinum-containing combination chemotherapy regimens. Patients with metastatic disease are allocated to either good-risk or poor-risk groups according to prognostic classifications or models.[1-3] The standard treatment for good...
Trichogerminoma is a rare neoplasm which was first described in 1992 and there is still controversy over its inclusion into the spectrum of trichoblastoma. A 79-year-old woman presented with a 5-year history of an asymptomatic nodule on the left posterior neck. Histologically, the lesion revealed a well-demarcated deep dermal nodule surrounded by a pseudocapsule. The tumor was composed of lobul...
Hyalinizying clear cell carcinoma is a rare tumor which affects women more than men and is more common in minor salivary glands. The purpose of this paper was to describe a case of hyalinizing clear cell carcinoma of buccal vestibule in a 55-year-old woman. It is important to differentiate this neoplasm from other tumors with clear cell features because of their differences in treatment and cli...
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy derived from plasmacytoid dendritic cells. There is currently no accepted standard of care for treating this neoplasm, and therapeutic strategies have never been prospectively evaluated. Since blastic plasmacytoid dendritic cell neoplasm cells express high levels of interleukin-3 receptor α chain (IL3-Rα or CD123), antitum...
Authors Amy Heerema-McKenney, MD* Department of Pathology, Stanford University, Palo Alto, California Jay Bowen, MS Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus, Ohio D. Ashley Hill, MD Department of Pathology, Children’s National Medical Center, Washington, DC Stephen J. Qualman, MD** Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus...
Testicular germ cell tumors are the most common malignancy among young men. These are highly chemo-sensitive tumors with high cure rates. More than 95% of patients with testicular cancer present with a painless testicular mass. Here we describe a rare initial presentation of testicular cancer in a previously asymptomatic 22-year-old male who presented with widespread metastatic cannonball lesio...
Background Sertoli cells located in seminiferous tubular basement membrane and surrounds different types of germ cell and they were only somatic cell type that directly contacts germ cells. These cells have Several role like support activities, nutrition of germ cells.During spermatogenesis, expression of SOX3 is necessary for differentiation of spermatogonia A. SOX3 is a transcription factor, ...
Primary cutaneous large B-cell lymphoma leg type is a rare andaggressive neoplasm as defined by the recently updated WorldHealth Organization - European Organization for Research andTreatment of Cancer. We report a case of an 80-year-old manwith multiple cutaneous lesions. Here, we review the availableliterature and summarize clinical features and management ofthis type of cutaneous B-cell lymp...
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