نتایج جستجو برای: genotyping assay

تعداد نتایج: 242708  

2010
ACA Deloof H De Wolf Y Verlinden J Villacian T Pattery

Background Assays that are used for the diagnosis and management of HIV-1 infection are subject to assay interference(s) and co-infection with HCV may interfere with HIV-1 genotyping and/or phenotyping. Since a third of HIV-1 infected patients are frequently HCV co-infected, there is an increasing need to assess the effect of HCV coinfection on the accuracy of the HIV-1 protease (PR) and revers...

Abdul Khaliq Naveed Shakir Khan, Tausif Ahmed Rajput Zia-Ur Rehman Farooqi

Objective(s):Organic anion transporter polypeptide 1B1 (OATP1B1) encoded by solute carrier organic transporter 1B1 (SLCO1B1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. Aim of this study was to investigate the frequencies of functionally significant SNPs (388A>G and 521T>C) and their haplotypes in 6 ethnic groups of ...

Journal: :Cold Spring Harbor symposia on quantitative biology 2003
J B Fan A Oliphant R Shen B G Kermani F Garcia K L Gunderson M Hansen F Steemers S L Butler P Deloukas L Galver S Hunt C McBride M Bibikova T Rubano J Chen E Wickham D Doucet W Chang D Campbell B Zhang S Kruglyak D Bentley J Haas P Rigault L Zhou J Stuelpnagel M S Chee

genetic factors underlying common disease are largely unknown. Discovery of disease-causing genes will transform our knowledge of the genetic contribution to human disease, lead to new genetic screens, and underpin research into new cures and improved lifestyles. The se-quencing of the human genome has catalyzed efforts to search for disease genes by the strategy of associating sequence variant...

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