The vertebrate organizer and notochord have conserved, essential functions for embryonic development and patterning. The restricted expression of developmental regulators in these tissues is directed by specific cis-regulatory modules (CRMs) whose sequence conservation varies considerably. Some CRMs have been conserved throughout vertebrates and likely represent ancestral regulatory networks, w...

This paper describes a technique for the recognition of off-line handwritten Arabic (Indian) numerals using Radon-Fourier-based features. A two stage classification scheme is used. The Nearest Mean (NMC), K-Nearest Neighbor (K-NNC), and Hidden Markov Models (HMMC) Classifiers are used in the first stage and a Structural Classifier (SC) is used in the second stage. A database of 44 writers with ...

K(ATP) channels are important for insulin secretion and depolarization of vascular smooth muscle. In view of the importance of drugs affecting K(ATP) channels in the treatment of diabetes, we investigated the effects of these channels on splanchnic blood perfusion in general and pancreatic islet blood flow in particular. We treated anesthetized Sprague-Dawley rats with the K(ATP) channel opener...

One of the most promising applications of hot water is aquaculture. Temperature is one of the most principle parameters affects aquaculture life. It can cause stress and mortality or superior environment for growth and reproduction. Shrimp is warm water aquaculture type need hot water supply. To increase pond production it is necessary to keep water temperature at 34C. Artificial intelligence (...

Recently, a metastable thermal-chemical convection model was proposed to explain the African Superplume. Its bulk tabular shape remains relatively stable while its interior undergoes significant stirring with low-velocity conduits along its edges and down-welling near the middle. Here, we perform a mapping of chemistry and temperature into P and S velocity variations and replace a seismically d...

The relationship between Boolean proof nets of multiplicative linear logic (APN) and Boolean circuits has been studied [Ter04] in a non-uniform setting. We refine this results by taking care of uniformity: the relationship can be expressed in term of the (Turing) polynomial hierarchy. We give a proofs-as-programs correspondence between proof nets and deterministic as well as non-deterministic B...

Phosphatidylinositol bisphosphate (PIP2) regulates the activities of many membrane proteins, including ion channels, through direct interactions. However, the affinity of PIP2 is so high for some channel proteins that its physiological role as a modulator has been questioned. Here we show that PIP2 is a key cofactor for activation of small conductance Ca2+-activated potassium channels (SKs) by ...

Many synthesis approaches for reversible and quantum logic have been proposed so far. However, most of them generate circuits with respect to simple metrics, i.e. gate count or quantum cost. On the other hand, to physically realize reversible and quantum hardware, additional constraints exist. In this paper, we describe cost metrics beyond gate count and quantum cost that should be considered w...

Stomach cancer, the second most common cancer in the world, represents a very important health problem with about 900,000 new cases diagnosed every year, and is a major cause of mortality in Chennai, India. Despite advances in diagnosis and treatment, the 5-year survival rate of stomach cancer is only 25 per cent (Terry et al, 2002). The aetiology of stomach cancer is multifactorial and predomi...