نتایج جستجو برای: genotype 6
تعداد نتایج: 1037231 فیلتر نتایج به سال:
BACKGROUND Black women are at greater risk for peripartum cardiomyopathy (PPCM). The guanine nucleotide-binding proteins β-3 subunit (GNB3) has a polymorphism C825T. The GNB3 TT genotype more prevalent in blacks is associated with poorer outcomes. We evaluated GNB3 genotype and myocardial recovery in PPCM. METHODS AND RESULTS A total of 97 women with PPCM were enrolled and genotyped for the G...
To determine salinity-tolerant genotypes among the citrus germplasm present in Kotra collection, a greenhouse experiment was carried out as factorial, completely randomized design with three replications, at four levels of NaCl (0, 2, 4 and 6 dS/m) and 10 unknown genotypes, for 16 weeks. Cleopatra mandarin and Swingle Citromelo, as tolerant (control) and sensitive cultivars, respectively, were ...
Recent studies have focused on genetic polymorphism of the interleukin-6 (IL-6) gene, which has led to a better understanding of the intricate interactions between host response, microorganisms, and genetics. Genotype prevalence appears to vary by the race and ethnicity of the population studied. We used a polymerase chain reaction technique to determine the prevalence of single nucleotide poly...
Osteoarthritis is a chronic progressive degenerative joint disease characterized by age-related regressive change in articular cartilage. A single nucleotide polymorphism has been described at position -174 of the interleukin-6 (IL-6) promoter region, leading to three possible genotypes, GG, GC, and CC. We investigated a possible association of the IL-6 -174G/C gene polymorphism with knee osteo...
Objective. To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 -174G/C polymorphism by PCR-RFLP. Therapeutic response was strictly defined: on...
Objective: This study aimed at investigating the agonistic interactions among goats in food competition based on genotype, horn and dominance rank. Material Methods: After determining rank of Maltese Turkish Saanen genotypes, a mixed group consisting horned, polled both horned animals, 2 to 5 years old, 54 heads total, nine each total 6 groups with linear social were formed. The observations ev...
OBJECTIVE Baseline concentrations of plasma C-reactive protein (CRP) are associated with coronary heart disease. Interleukin-6 (IL-6) regulates CRP gene expression; a promoter polymorphism (-174G/C) of the IL-6 gene has been shown to influence IL-6 transcription but the relationship between genotype at this polymorphism and circulating levels of inflammatory markers remains unclear. We hypothes...
OBJECTIVE To determine Sustained Viral Response (SVR) to Interferon (IFN) and ribavirin therapy in chronic hepatitis C patients of genotype 2 and 3. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Garden Clinic, Lahore, from June 1997 to August 2007. METHODOLOGY All patients of both genotypes 2 and 3 receiving combination therapy were included. Standard IFN with ribavirin was st...
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