Crosslinked chitosan-based nanofilms (thickness approximately 40 nm) were prepared using a naturally occurring and nontoxic reagent, genipin, the surface properties studied as function of crosslinking degree pH, by combining three techniques: dynamic contact angle sessile drops, quartz crystal microbalance with dissipation (QCM-D) atomic force microscopy (AFM). The results showed pH-response th...

Enzyme immobilization is necessary process to improve the bioactivity and stability of biocatalyst. In this study, glucose oxidase (GOx) enzyme was immobilized on plasma-treated fibrous carbon felt as a textile carrier produce heterogeneous catalyst. Genipin, naturally occurring crosslinker, that has less cytotoxicity than conventional crosslinkers, used in process. UV-Vis FTIR spectra confirme...

To verify the anti-inflammatory potency of iridoids, seven iridoid glucosides (aucubin, catalpol, gentiopicroside, swertiamarin, geniposide, geniposidic acid and loganin) and an iridoid aglycone (genipin) were investigated with in vitro testing model systems based on inhibition of cyclooxygenase (COX)-1/-2 enzymes, the tumor necrosis factor-α (TNF-α) formation and nitric oxide (NO) production. ...

The present review article intends to direct attention to the technological advances made since 2009 in the area of genipin-crosslinked chitosan (GEN-chitosan) hydrogels. After a concise introduction on the well recognized characteristics of medical grade chitosan and food grade genipin, the properties of GEN-chitosan obtained with a safe, spontaneous and irreversible chemical reaction, and the...

Background: Galactomannans are the seed polysaccharides also known as gums, mostly isolated from legume endosperm. can easily mix with xanthans by physical association, exhibits synergistic effect and form complex mixtures due to their entangle nature in deferent ratios. Polysaccharides having these properties make them versatile materials which useful different biomedical food applications add...

The antimicrobial activity of a wound dressing is a key factor for preventing and treating wound infection. The current study evaluated the physiochemical properties and antimicrobial activities of semi-IPNs (interpenetrating polymer networks) based on chitosan/polyvinyl alcohol (PVA) films and nanofibers as candidates for wound dressings and investigated the effects of morphologies (nanofibrou...

“Lianzhifan solution” (LZF) is produced by the natural fermentation of coptis root and gardenia fruit, it a classic prescription for external use in anorectal department. During process, structural evolution microbial communities led to significant changes chemical profile. In this study, we first analyzed dynamic components as well composition succession community during whole process LZF, con...