What is genetically engineered food? Genetically engineered (GE) food is produced from plants, animals, and microbes that have had their genetic code modified by the selective introduction of specific DNA segments through the use of gene splicing. This process allows the organism to acquire a desirable trait such as pest protection, herbicide resistance, or improved nutritional qualities. Foods...

We investigated the prevalence of Helicobacter hepaticus, murine norovirus (MNV), and Pneumocystis carinii and the efficacy of cross-fostering for their eradication in 49 genetically engineered mouse (GEM) strains at our institute. Prevalences of H. hepaticus, MNV, and P. carinii were 33.9, 36.5, and 8.6%, respectively, and immunodeficient strains showed relatively higher prevalence of the 3 pa...

Both chronic calorie restriction (CCR) and intermittent calorie restriction (ICR) have shown anticancer effects. However, the direct evidence comparing ICR to CCR with respect to cancer prevention is controversial and inconclusive. PubMed and Web of Science were searched on November 25, 2015. The relative risk (RR) [95% confidence interval (CI)] was calculated for tumor incidence, and the stand...

A biosensor is an analytical device which integrates a biological recognition element with a physical transducer to generate a measurable signal proportional to the concentration of the analyses. A microbial biosensor consists of a transducer in conjunction with immobilized viable or non-viable microbial cells. Non-viable cells obtained after Permeable or whole cells containing periplasmic enzy...

BACKGROUND Engineered blood has the greatest potential to combat a predicted future shortfall in the US blood supply for transfusion treatments. Engineered blood produced from hematopoietic stem cell (HSC) derived red blood cells in a laboratory is possible, but critical barriers exist to the production of clinically relevant quantities of red blood cells required to create a unit of blood. Ery...

Objective(s): Filamentous bacteriophage M13 was genetically engineered to specifically target mammalian cells for gene delivery purpose. Materials and Methods: A vascular endothelial growth factor receptor 2 (VEGFR2)-specific nanobody was genetically fused to the capsid gene III of M13 bacteriophage (pHEN4/3VGR19). A mammalian expression construct containing Cop-green fluorescent protein (Cop-G...

The development of genetic technologies and bioengineering are creating an increasing number genetically engineered microorganisms with new traits for diverse industrial applications such as vaccines, drugs pollutant degraders. However, the destiny bacterial spores released into environment long-life organisms has remained a big environmental challenge. In this study, environmentally responsibl...

Abstract Microorganisms serve as agents for synthetic biology. It certain instances, the technology is reliant on survival of genetically-altered microorganism in natural environment. This chapter offers insight into soil system to improve performance microorganisms covers system, fitness genetically altered organisms, and considerations their proliferation nature. does not discuss ecological c...

Drug development and preclinical trials are challenging processes and more than 80% to 90% of drug candidates fail to gain approval from the United States Food and Drug Administration. Predictive and efficient tools are required to discover high quality targets and increase the probability of success in the process of new drug development. One such solution to the challenges faced in the develo...