OBJECTIVE Identify the biological, social, and economic conditions influencing the knee height/stature index (KHSI) in growing individuals of Maya ancestry in the city of Merida, Yucatan, Mexico. METHODS The hypothesis was that KHSI values would be lower in subjects with two Maya surnames. This was tested by analyzing the effect of a series of environmental, biological, and socioeconomic vari...

Background: Short children face many problems throughout their lives. Consumption of growth hormone and the drugs such as Letrozole, Oxandrolone, and Anastrozole can increase the growth of children and adolescents. There is not an overall estimate of the effects of Letrozole, Oxandrolone, and Anastrozole on the growth of children and adolescents with Idiopathic Short Stature (ISS). There are di...

FGFR3 (fibroblast growth factor receptor 3) is a gene responsible for the most common form of osteodysplasia, achondroplasia, which results in extreme short stature. An allelic disorder, hypochondroplasia, however, presents with a much milder phenotype and is sometimes indistinguishable from idiopathic short stature. In this study, in order to test the possibility of the mildest end of hypochon...

Short stature is a common concern for physicians caring children. In traditional investigations, about 70% of children are healthy, without producing clinical and laboratory findings that justify their growth disorder, being classified as having constitutional short or idiopathic (ISS). such scenarios, the genetic approach has emerged great potential method to understand ISS. Over last 30 years...

AIM To study the etiological profile of short stature at a tertiary care hospital in north India. METHODS In this prospective study, 176 children with short stature were enrolled from January 2005 to December 2006. Appropriate screening and definitive tests were performed to establish the etiology of short stature. RESULTS Celiac disease (CD) emerged as the single most common (15.3%) cause ...

More than 1200 St Helenian schoolchildren were studied in 1973 and 1978 to determine how social factors affected growth. The association of short stature with large family size was confirmed and shown to be concentrated in the earlier members of the sibship. This was independent of birth interval. Association between birth interval and stature was most pronounced for the spacing following the i...

BACKGROUND Perinatal undernutrition may lead to important metabolic adaptations in adult life, short stature being the most visible. The present study aimed to evaluate the association between stature and total energy expenditure of low-income women. METHOD Women aged 19-45 years from low-income communities in Maceió-AL were recruited. A sample of 67 volunteers was selected and divided into e...

Few paediatricians would deny that children with extreme short stature face a disability that may affect their physical, psychological, and social well being. Though considerable research has been performed on the nature of this disability, it has been focused on patients who are very short, secondary to conditions such as growth hormone deficiency or achondroplasia, and are attending specialis...