background : alzheimer's disease (ad) is one of the most common problems for old peoples. etiology of ad is not clear, but genetic factors play a major role in determining a person's risk to develop ad. twin and family studies con-firm that ad has a genetic basis.ad genetics has been split into two broad categories: early-onset and late-onset. eo-ad cases are inherited in an autosomal dominant ...

thrombophilia increases the incidence of pulmonary thrombosis significantly. various hereditary and acquired factors are known for thromboembolism. the hereditary factors are two common genetic autosomal mutations including factor v leidan mutation and prothrombin gene mutation. a descriptive- analytical design was conducted on 60 patients with thromboembolism who met the inclusion criteria. tw...

Several sleep disorders have a genetic basis. These conditions include the narcoleptic syndrome, sleep walking, periodic movements in sleep, circadian delay syndromes and familial insomnia. These disorders illustrate different control mechanisms involved in sleep and wakefulness, including those determining the prevalence and timing of NREM and REM activity, somatomotor inhibition and excitatio...

It is estimated that each 25%-30% in the variability in the incidence of malaria can be attributed to genetic and environmental factors, respectively. In various study designs on the different types of manifestation of Plasmodium falciparum infection, associations between genetic polymorphisms and malaria are examined. The selection of polymorphisms under study follows hypotheses on the role of...

A number of genetic loci have been identified that appear to be associated with systemic sclerosis (SSc; scleroderma). There is mounting evidence suggesting that these genetic associations may in fact be associated with distinct phenotypes in SSc based on autoantibody pattern rather than with SSc as a single disease entity. This may ultimately have implications for approaches to therapy as well...