autistic disorders (ads) are neuro-developmental disorders in the category of pervasive developmental disorders chiefly described by three main deficits: 1) deviant communication, 2) impaired reciprocal social interaction, and 3) limited, repetitive and stereotypic patterns of behaviors or interests 1. the world-wide prevalence of ads is estimated to be 62/10,000 1. although various treatment r...

ône-third of population deal with sleep disorders which might be due to social, economic or medical problems. studies on twins have indicated the role of genetic factors in these disorders. monozygotic twins have a very similar hypnogram. â higher prevalence of some sleep disorders is reported in relatives of the patients with these disorders. genes also affect sleep disorders as well as some o...

background cystic fibrosis is a complex progressive disease which assessing its progression and severity is essential. for this purpose there are scoring systems available to evaluate the disease severity. objectives the aim of the present study was to determine the clinical status of cf patients using shwachman score system in the pediatric pulmonary ward of masih daneshvari hospital. patients...

background: brucella is a gram-negative bacterium, causing acute and chronic infection in humans and animals. cell-mediated immunity is the main protective immune response against brucella spp. activation of macrophages by ifn-γ and generation of reactive oxygen intermediates and nitric oxide are the main immunologic mechanisms responsible for control of brucella infection. objective: to invest...

objective: low density lipo-protein receptor- related protein (lrp) is the most important cholesterol receptor in neurons. it serves as a receptor for apoe protein which is the most important risk factor for alzheimer’s disease. lrp also contributes to the ligation of lipoproteins with apoe in neurons. association between lrp c766t and alzheimer’s disease in iranian patients with late onset alz...

background:  the development of allergic rhinitis (ar) is caused by the interaction between genetic predisposition and environmental factors. in this study, the association between gata3 single nucleotide polymorphisms and ar in an iranian population was identified. methods:  this case-control study was performed on 86 patients with ar and 86 healthy subjects. this study aimed to evaluate a pot...

background: campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. the aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of campylobacter spp. strains isolated from patients and f...