نتایج جستجو برای: generic granisetron
تعداد نتایج: 76036 فیلتر نتایج به سال:
Nausea and vomiting are typical side effects of cytotoxic therapy and some surgical procedures. These symptoms can represent a major therapeutic challenge and, if inadequately controlled by antiemetic treatment, will result in increased mortality, morbidity, and health care costs. However, the management of nausea and vomiting has improved greatly in recent years following the introduction of t...
STUDY OBJECTIVE To evaluate the efficacy and safety of aprepitant added to standard antiemetic regimens used in high-dose chemotherapy for allogeneic hematopoietic stem cell transplantation (allo-HSCT). DESIGN Retrospective medical record review. SETTING Hematology ward of a university hospital in Japan. PATIENTS Of 88 patients treated with high-dose chemotherapy followed by allo-HSCT, 46...
For patients receiving high-dose chemotherapy, a 5-hydroxytryptamine 3 receptor antagonist combined with dexamethasone is a standard antiemetic therapy. Despite this prophylactic anti-emetic treatment, many patients still suffer from uncontrollable emesis. In this study, we retrospectively evaluated the antiemetic effectiveness and safety of aprepitant (a neurokinin-1 receptor antagonist) in ad...
the purpose of the present study was to explore the passive and electrically assisted transdermal transport of granisetron hydrochloride (gra) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. in this study, iontophoretic permeation of gra through guinea pig skin...
Use of cisplatin as a chemotherapeutic agent causes acute and delayed emesis. Kaolin, saccharin solution and normal feed consumption have been evaluated as an index of cisplatin-induced emesis in rats; however, the most preferable of these methods for evaluating the various phases of emesis remains unclear. In the current study, kaolin, saccharin solution and normal feed consumption following c...
Granisetron content of some pharmaceutical tablets was determined using a novel all-solid-state polymeric-membrane-electrode (ASS-PME) having a sensing element functioning based on an ion-exchange mechanism. The best results were observed with ASSPMEs containing 8% GST-tetrakis (p-chlorophenyl) borate as the ion-pair, 56% of dibutyl phthalate, 31% of poly(vinyl chloride), 3% of an ionic liquid ...
Objective: To determine the effectiveness of intravenousinjection granisetron compared to ondansetron inpreventing nausea and vomiting, we used MASCCAntiemesis Tool (MAT) in ovarian cancer patients undergoingpaclitaxel-carboplatin chemotherapyMethods: This study was conducted as a double-blind,randomized controlled trial. The treatment group received1 mg granisetron, whereas control received8 i...
A 63-year-old man with lung carcinoma and no history of contact dermatitis presented an intense erythematopapular eruption on his arms, back, and groin after a 3-day course of corticosteroids following chemotherapy. He had tolerated an initial chemotherapy cycle with paclitaxel and cisplatin well. The patient had received the following drugs: cisplatin, paclitaxel, granisetron, bemiparin, osmof...
Nowadays, many drug groups are available for prophylaxis and treatment of post-operative nausea and vomiting(PONV). These drugs can have different effects on individual patients and surgical procedures. Additionally, some of these drugs are expensive and this can be a limiting factor in their selection. Moreover, no exact protocol exists for the use of these drugs. Due to the involvem...
this study purported to compare and contrast the use of self-mention and evidentials as two mtadiscourse features in opinion columns of persian and english newspapers. the theoretical basis of this study is the idea that metadiscourse features vary across cultural boundaries. for this purpose, 150 persian and 150 english opinion columns were collected based on three factors of topic, audience a...
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