Abstract. The choice of hyper-parameters (e.g. kernel parameters) can significantly affect generalization performance of large margin classifiers. In this paper we are concerned with the problem of tuning these values in the case of multi-class problems that have been recast into a set of binary problems. We report several experimental results comparing independent and joint tuning of the hyper...

hyper-tubes consisting of hyper-cubes of n-dimensions were designed and formulas for substructures of vary dimensions established.

Thirty-seven adults (19 male, 18 female) with mitral valve prolapse (MVP) were examined for evidence of joint hypermobility scored on a 0-9 scale. None of the patients had hypermobility scores exceeding 3, and comparison with 37 healthy age and sex matched controls recruited from hospital staff failed to show an increased prevalence of hypermobility in MVP. There was no evidence that the MVP sy...

Stiff skin syndrome is a rare scleroderma-like disorder of unknown etiology characterized by stone-hard indurations of skin, mild hypertrichosis and limited joint mobility. No effective treatment has yet been found. Exercises and rehabilitative therapy are important in maintaining the patient's quality of life. The authors present a case of a two-year-old boy with progressive skin hardening sin...

The condition of chronic instability of the MP (metacarpophalangeal) joint of the thumb, may be the resultant of chronic strain of the ulnar collateral ligament of the MP joint. This condition was described in Scottish gamekeepers who used to kill hunted animals by a special manoeuvre subjecting the thumb to extension abduction force, and was termed "Gamekeeper's Thumb" (Campbell, 1955). Nowada...

BACKGROUND Joint pain is a highly prevalent condition in the older population. Only a minority of the older adults consult the general practitioner for joint pain, and during consultation joint pain is often poorly recognized and treated, especially when other co-existing chronic conditions are involved. Therefore, older adults with joint pain and comorbidity may have a higher risk of poor func...

Joint mobility was assessed in 80 consecutive adult noninsulin-dependent diabetic (NIDD) patients and 47 nondiabetic controls matched for age and sex. Impairment of mobility was observed in 36 NIDD patients but only 7 controls (p less than 0.01). There was no significant differences between diabetic patients with and without impaired mobility with regards to age, duration of diabetes, mean dail...

BACKGROUND There are a number of indications for total joint replacement surgery, mainly degenerative changes with limited function, rheumatoid arthritis, post-traumatic changes, arthropathy accompanying rotator cuff injuries. Problems in the rehabilitation of patients following partial or total shoulder joint replacement surgery result from the anatomy and biomechanics of the shoulder, includi...

Ligament injuries are among the most common causes of musculoskeletal joint pain and disability encountered in primary practice today. Ligament injures create disruptions in the balance between joint mobility and joint stability, causing abnormal force transmission through the joint, which results in damage to other structures in and around the joint. The long-term consequence of nonhealed liga...