نتایج جستجو برای: gene regulatory networks

تعداد نتایج: 1656653  

2009
Chushin Koh Fang-Xiang Wu Gopalan Selvaraj Anthony J. Kusalik

Computational gene regulation models provide a means for scientists to draw biological inferences from time-course gene expression data. Based on the state-space approach, we developed a new modeling tool for inferring gene regulatory networks, called time-delayed Gene Regulatory Networks (tdGRNs). tdGRN takes time-delayed regulatory relationships into consideration when developing the model. I...

Journal: :Mathematical biosciences and engineering : MBE 2008
David Iron Adeela Syed Heidi Theisen Tamas Lukacsovich Mehrangiz Naghibi Lawrence J Marsh Frederic Y M Wan Qing Nie

In this paper, we consider a mathematical model for the formation of spatial morphogen territories of two key morphogens: Wingless (Wg) and Decapentaplegic (DPP), involved in leg development of Drosophila. We define a gene regulatory network (GRN) that utilizes autoactivation and cros-sinhibition (modeled by Hill equations) to establish and maintain stable boundaries of gene expression. By comp...

Journal: :Transactions of the Society of Instrument and Control Engineers 2012

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