Gene tree correction has recently gained interest in phylogenomics, as it gives insights in understanding the evolution of gene families. Following some recent approaches based on leaf edit operations, we consider a variant of the problem where a gene tree is corrected by inserting leaves with labels in a multiset M . We show that the problem of deciding whether a gene tree can be corrected by ...

Infectious bursal disease virus (IBDV) is the causative agent of Gumboro disease, an infectious disease of global economic importance in poultry. Structural protein VP2 of IBDV is the most frequently studied protein due to its significant roles in virus attachment, protective immunity, and serotype specificity. The objective of the present study was to improve the expression of hypervariable re...

Background: Cystic echinococcosis (CE), as a chronic parasitic disease, is a major health problem in many countries. The performance of the currently available serodiagnostic tests for the diagnosis of CE is unsatisfactory. Objective: The current study aimed at sub-cloning a gene, encoding the B8/1 subunit of antigen B (AgB) from Echinococcus granulosus, using gene optimization for the immunodi...

background and aims: plant certification programs need reliable, fast, cheap and sensitive methods for detection of systemic pathogens with special interest in virus and viroid detection. reverse transcriptase-polymerase chain reaction (rt-pcr) has been documented as an alternative assay for certification of plant propagating materials. the main object of the present study was the optimization ...

In this paper a new technique for the solutions of hard computational problems in bioinformatics is investigated. This is the $-calculus process algebra for problem solving that applies the cost performance measures to converge to optimal solutions with minimal problem solving costs. We demonstrate that the $-calculus generic search method, called the kΩ-optimization, can be used to solve gene ...