Sarin is a very toxic organophosphorus chemical warfare agent which has been used in different wars. According to an immediate demand of detection, secure approachs to break down this toxic nerve agent, the study on decomposition of sarin achieve significance. In this work, we have made endeavors of discovering an approach to neutralize this hazardous kind by adsorption of this molecule by C20 ...

We propose the sequencing of 9 chordate species to complete the coverage of all major nodes of chordate evolution with at least two sequenced species. These include; 1. Reptile 1: Alligator mississipiensis (2.5 Gb genome), the American alligator, for high quality draft genomic sequence (approx. 6x) plus ESTs. 2. Reptile 2: Chrysemys picta (2.6 Gb genome), the painted turtle, for high quality dr...

The in vivo and in vitro experiments were performed on forty dogs to assess the accuracy and to compare three methods estimating gallbladder (GB) volume. During in vivo experiments, fasting GB volumes in normal dogs were compared with dogs exhibiting GB wall thickness. Another group of dogs with the GB shapes resembling the ellipsoid was studied in vivo and in vitro. First, the ellipsoid method...

Glioblastoma (GB) remains the most aggressive primary brain malignancy. Adoptive transfer of chimeric antigen receptor (CAR)-modified immune cells has emerged as a promising anti-cancer approach, yet the potential utility of CAR-engineered natural killer (NK) cells to treat GB has not been explored. Tumors from approximately 50% of GB patients express wild-type EGFR (wtEGFR) and in fewer cases ...

Grain boundaries (GBs) can undergo first-order or continuous phase-like transitions, which are called complexion transitions. Such GB transitions can cause abrupt changes in transport and physical properties, thereby critically influencing sintering, grain growth, creep, embrittlement, electrical/thermal/ionic conductivity, and a broad range of other materials properties. Specifically, the pres...

Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host immunity. Instead, it seems that class II presentation of endogenous HCMV antigens in these cells allows recognition of virus infection. We characterized class II presentation of HCMV glycoprotein B (gB), a...

Herpesviruses use gB and gH-gL glycoproteins to execute fusion. Other virus-specific glycoproteins are required for receptor binding and fusion activation. The human cytomegalovirus (HCMV) UL131-128 proteins are essential for the infection of leukocytes, endothelial cells (ECs), and many epithelial cell lines. Here we show that UL131-128 play a role in a chain of events involving gB and gH duri...

Recent studies have shown that counting citations from books can help scholarly impact assessment and that Google Books (GB) is a useful source of such citation counts, despite its lack of a public citation index. Searching GB for citations produces approximate matches, however, and so its raw results need timeconsuming human filtering. In response, this article introduces a method to automatic...

Herpesviruses characteristically transmit infection from immune hosts. Although their success in escaping neutralization by pre-formed antibody is indisputable, the underlying molecular mechanisms remain largely unknown. Glycoprotein B (gB) is the most conserved component of the herpesvirus entry machinery and its N terminus (gB-NT) is a common neutralization target. We used murid herpesvirus-4...

PURPOSE Gallbladder (GB) wall thickening can be found in various conditions unrelated to intrinsic GB disease. We investigated the predisposing etiologies and the outcome of acalculous GB wall thickening in children. METHODS We retrospectively analyzed 67 children with acalculous GB wall thickening who had visited our institute from June 2010 to June 2013. GB wall thickening was defined as a ...