Current evidence suggests that there are three sphincters that regulate the flow of chyme from stomach to the duodenum. We investigated the hypothesis whether a fourth 'physiologic sphincter' exists at the duodeno-jejunal junction. The pressure response of the jejunum, duodeno-jejunal junction and duodenum to individual balloon distension of the jejunum and duodenum was recorded in 28 healthy s...

Heat at the junction of light-emitting diodes (LED) affects the overall performance of the LED in terms of light output, spectrum, and life. Usually it is difficult to measure junction temperature of a LED directly. There are several techniques for estimating LED junction temperature. One-dimensional heat transfer analysis is one of the most popular methods for estimating the junction temperatu...

The gap junction connecting cardiac myocytes is voltage and time dependent. This simulation study investigated the effects of dynamic gap junctions on both the shape and conduction velocity of a propagating action potential. The dynamic gap junction model is based on that described by Vogel and Weingart (J. Physiol. (Lond.). 1998, 510:177-189) for the voltage- and time-dependent conductance cha...

ureteral obstruction is relatively common after renal transplantation. a rare cause is the inguinal herniation of the transplant ureter. we report a case of late allograft renal transplant failure due to ureteral herniation as well as ureterovesical junction stenosis.

The two-leg ladder system consisting of the Kitaev chains is known to exhibit a richer phase diagram than that single chain. We theoretically investigate variety Josephson effects between systems. consider difference $\theta$ these two systems as well $\phi$ parallel in each system. total energy junction at $T = 0$ calculated by numerical diagonalization method functions $\theta$, $\phi$, and a...

It is shown that a theorem on essential gyrators presented by Rosenberg (1) and used in (2) claims too much and that the internal structure ofthe multiport elements ofthe system must be studied in order to be able to decide whether a gyrator is essentially contained in the system or not. Bond graph terminology is used (3H6) an d a new theorem is formulated, which provides un algorithm to decide...

Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a main driver of metastatic spread. We show here that Metastasis suppressor-1 (Mtss1; Missing in Metastasis, MIM), a member of the IMD-family of proteins, inhibits cell-cell junction disassembly in wound healing or HGF-induced scatter assays b...

Nanomultiple CaFe2O4/ZnFe2O4pn junctions are prepared by a pulsed laser deposition method to explore their photoelectrochemical properties as the photoelectrodes. It is demonstrated that the multiple-pn-junction structure is favorable to enhancing the photocurrent density and the onset potential of the photoelectrode. Furthermore, the 20-junction photoelectrode-based PEC cell yields a high open...

The results presented in this study establish an association between phospholipase C-beta (PLC-beta) and tight junction permeability across Madin-Darby canine kidney (MDCK) cell monolayers, an in vitro model for epithelial tissue. These results further show that PLC-beta modulates tight junction permeability by affecting actin filament organization. Hexadecylphosphocholine (HPC) inhibited PLC-b...

Two archaeal Holliday junction resolving enzymes, Holliday junction cleavage (Hjc) and Holliday junction endonuclease (Hje), have been characterized. Both are members of a nuclease superfamily that includes the type II restriction enzymes, although their DNA cleaving activity is highly specific for four-way junction structure and not nucleic acid sequence. Despite 28% sequence identity, Hje and...