In view of surgery, GERD is the failure of the antireflux barrier, allowing abnormal reflux of gastric contents into the esophagus. It is a mechanical disorder, which is caused by a defective lower esophageal sphincter (LES), a gastric emptying disorder, or failed esophageal peristalsis. These abnormalities result in a spectrum of disease ranging from symptoms only, such as "heartburn", to esop...

Gastro-esophageal reflux disease (GERD) in otherwise healthy older children and adolescents is commonly encountered in pediatric clinics and poses a complex treatment problem involving changes of diets and lifestyle. After an initial history taking and a physical examination, typical symptoms of GERD in older children and adolescenct are initially treated with the trials of acid suppressants. W...

BACKGROUND Gastro-esophageal reflux disease (GERD) predisposes to airway disease through a vagally-mediated esophago-bronchial reflex. This study investigates this vagal response to esophageal acid perfusion. METHODS 40 asthmatics with mild stable asthma participated. Each subject underwent spirometry and autonomic function testing (valsalva maneuver, heart rate response to deep breathing and...

AIM The aim of this study was to evaluate the epidemiology of GERD base on population study in Tehran providence. BACKGROUND Gastro-esophageal reflux disease (GERD) is a common and chronic problem. Recent reports from developing countries indicate increment in the incidence and prevalence of the disease over the past. PATIENTS AND METHODS This study was a cross-sectional household survey co...

Introduction: Gastro-esophageal reflux disease (GERD) is present when repeated backflow of gastric contents into the esophagus causes chronic symptoms or damages the esophageal lining. In recent years, the prevalence of GERD has increased and there is a strong correlation between acid reflux and the increasing incidence of esophageal cancer [1]. The gastro-esophageal junction (GEJ) is the key d...