Background: Gallstone disease or cholelithiasis, is one of the most common surgical problems worldwide. The assessment of gallbladder kinetics in patients with cholelithiasis as well as in patients with high risk for cholelithiasis could play a significant role in better management and is recommended as a routine workup of biliary system in these patients. Objectives: This study was carried out...

BACKGROUND AND AIMS Even if the motor activity of the gall bladder and sphincter of Oddi (SO) are integrated, it is not known if the presence of stones in the gall bladder affects SO function. The aim of the study was to compare SO motor activity in patients with and without gall stones. PATIENTS AND METHODS In a series of 155 patients consecutively submitted to endoscopic retrograde cholangi...

BACKGROUND Cholecystectomy through laparotomy with or without intra-peritoneal drain has been the standard operation for the gall bladder disease for the last 100 years. It implies removal of gall bladder and is performed mainly for symptomatic gall stones. The Objectives was to analyse the outcome of open cholecystectomy without drain in term of complications. METHODS Patients who underwent ...

BACKGROUND Gallbladder agenesis (GA) is an extremely rare anatomic anomaly with a reported incidence of less than 0.5%. It is usually asymptomatic, but can present with features of biliary colic and cholecystitis. We present here a case of GA in a patient with recurrent biliary colic.  CASE REPORT A 24-year-old African American woman presented with recurrent episodes of right upper-quadrant abd...

1. Electrical potential differences (p.d.'s) have been measured across an in vitro preparation of rabbit gall-bladder.2. When the gall-bladder separates identical bathing solutions, the p.d. is always zero, regardless of the composition of the bathing solution. Hence the gall-bladder is symmetrical: i.e. the mucosal and serosal cell membranes have the same relative permeability coefficients.3. ...

OBJECTIVE: To see the outcome of early laparoscopic Cholecystectomy in acutely inflamed gall bladder. STUDY DESIGN: A prospective interventional study. st th PLACE & DURATION: Surgery unit-I of Fauji Foundation Hospital, Rawalpindi from 1 January 2005 to 30 June 2009. METHODOLOGY: Patients admitted with acutely inflamed gall bladder within 72 hrs of symptoms were subjected to early laparoscopic...

Disseminated blood borne metastases from carcinoma of the gall bladder are uncommon and occur late in the course of the disease. Of all the distant sites that can be involved by the metastatic disease, the skeletal system is the least commonly involved. Skeletal metastasis in a case of carcinoma gall bladder is rare to find and when it is associated with solitary skull metastasis it is even rar...

Background and aims—Even if the motor activity of the gall bladder and sphincter of Oddi (SO) are integrated, it is not known if the presence of stones in the gall bladder aVects SO function. The aim of the study was to compare SO motor activity in patients with and without gall stones. Patients and methods—In a series of 155 patients consecutively submitted to endoscopic retrograde cholangiopa...

Gall bladder perforation is a rare complication of cholecystitis. A definitive diagnosis is uncommon before surgery and the morbidity and mortality associated with this condition are high. We report six patients with gall bladder perforation to show the difficulty of making an early diagnosis. The history and the clinical findings of these patients are reviewed to highlight diagnostic pitfalls.

Idiopathic myelofibrosis is often associated with myeloid metaplasia (extramedullary haemopoiesis) in the spleen and liver. However, the gall bladder is an extremely unusual site for it to occur. A 59 year old man with myelofibrosis, who underwent cholecystectomy for chronic cholecystitis, showed myeloid metaplasia in his gall bladder. Pathologically, this may lead to diagnostic difficulties.