Induction of gene expression in response to DNA damage is important for repairing damaged DNA for cell survival. Previously, we identified a novel zinc finger protein, ZBRK1, which contains a KRAB domain at the N terminus, eight zinc fingers at the center, and a BRCA1-binding region at the C terminus. In a BRCA1-dependent manner, ZBRK1 represses Gadd45a transcription through binding to a specif...

To increase our current knowledge on the nutritional regulation of growth and gene expression pattern in fish skeletal muscle, effect dietary macronutrient composition was assessed digestibility, nutrient retention, performance, mRNA levels key genes involved functionality, development muscle gilthead sea bream (Sparus aurata). Long-term starvation decreased myogenic regulatory factors such as ...