Strobilurins are one of the most important classes of agricultural fungicides. To discover new strobilurin derivatives with high activity against resistant pathogens, a series of novel β-methoxyacrylate analogues were designed and synthesized by integrating substituted pyrimidine with a strobilurin pharmacophore. The compounds were confirmed and characterized by infrared, H nuclear magnetic res...

Based on our initial design, we synthesized two series of coumarin ring-opening derivatives by the reactions of hydrolysis and methylation. Results of antifungal screening in vitro showed that the target compounds exhibited potent activity against the six common pathogenic fungi. Compounds 6b, 6e, 6g, 6i, 7b and 7c were identified as the most active ones, and the EC50 values of these active com...

A series of pyrazole carboxamide and isoxazolol pyrazole carboxylate derivatives were designed and synthesized in this study. The structures of the compounds were elucidated based on spectral data (infrared, proton nuclear magnetic resonance and mass spectroscopy). Then, all of the compounds were bioassayed in vitro against four types of phytopathogenic fungi (Alternaria porri, Marssonina coron...

The effect of fungicides on silkworm larvae was analyzed with regard to the fact that these beneficial insects are usually affected by fungicides, Daily feeding on 1 and 2g/liter of carbendazim, a systemic fungicide, did not have significant effects on larval and pupal mortality. However the weight of the treated larvae showed considerable weight decrease up to 37% weight.. All the economic tra...

in this study, anti alternaria solani effects of essential oils of 11 medicinal and aromatic plant species belonging to four families collected from the west of iran were investigated based on agar dilution method with five replications at concentration of 1.0 µl/ml. the results showed that the highest inhibitory effect belonged to oliveria decumbens, cinnamomum zeylanicum, carum copticum and t...