نتایج جستجو برای: fungicidal activity

تعداد نتایج: 1135259  

Journal: :Journal of medical microbiology 2006
Emer P Reeves Markus Nagl Joseph O'Keeffe Judy Kelly Kevin Kavanagh

The fungistatic and fungicidal activity of N-chlorotaurine (NCT), a long-lived oxidant produced by stimulated neutrophils, was investigated. Physiological concentrations (75-100 microM) of NCT showed clear fungicidal activity against a range of Aspergillus isolates. Moreover, killing by NCT was significantly increased in the presence of ammonium chloride, explained by the formation of monochlor...

Journal: :Cytokine 2008
Elisandra Garcia Tavian Luciane Alarcão Dias-Melicio Michele Janegitz Acorci Ana Paula Bordon Graciani Maria Terezinha Serrão Peraçoli Angela Maria Victoriano de Campos Soares

Interleukin-15 is a cytokine produced by a wide range of different cell types, including macrophages, in response to lipopolysaccharide or microbial infection. This cytokine may play a crucial role in the activation of phagocytic cells against pathogens, especially during innate immune response. The effects of IL-15 on human polymorphonuclear leukocyte fungicidal activity against a highly virul...

Journal: :Asian Pacific journal of tropical biomedicine 2011
S Balakumar S Rajan T Thirunalasundari S Jeeva

OBJECTIVE To evaluate the in vitro antifungal activity of Aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis, Microsporum gypseum and Epidermophyton floccosum. METHODS The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and frac...

Journal: :Antimicrobial agents and chemotherapy 1989
A Reuben E Anaissie P E Nelson R Hashem C Legrand D H Ho G P Bodey

The MICs and minimum fungicidal concentrations of amphotericin B, natamycin, miconazole, itraconazole, and flucytosine against 17 isolates of Fusarium solani, 14 isolates of Fusarium moniliforme, 10 isolates of Fusarium oxysporum, and 3 isolates of Fusarium semitectum were determined by a broth microdilution method. Amphotericin B and natamycin were the most active agents tested and failed to s...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008
Nicky Longley Conrad Muzoora Kabanda Taseera James Mwesigye Joselyne Rwebembera Ali Chakera Emma Wall Irene Andia Shabbar Jaffar Thomas S Harrison

BACKGROUND Therapy for human immunodeficiency virus (HIV)-associated cryptococcal meningitis in many centers in Africa is fluconazole administered at a dosage of 400-800 mg per day. However, higher dosages of fluconazole have been used to treat patients without resulting in serious toxicity. Pharmacokinetic and pharmacodynamic considerations suggest that higher dosages might be associated with ...

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