The relationship between changes in functional magnetic resonance imaging and neuronal activity remains controversial. Data collected during awake neurosurgical procedures for the treatment of epilepsy provided a rare opportunity to examine this relationship in human temporal association cortex. We obtained functional magnetic resonance imaging blood oxygen dependent signals, single neuronal ac...

Objective: To evaluate the efficacy of blood oxygen level–dependent functional magnetic resonance imaging in the preoperative mapping of sensorimotor cortices and language areas, and its impact on surgical decisions. Methods: Fourteen patients with tumours or vascular malformations underwent functional magnetic resonance imaging (in the course of motor, sensory, and language tasks) and had stru...

Objective(s): Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with ahigh frequency. However, there is no data on the correlation of cognitive...

Glossary Block Design: Experimental design for functional neuroimaging in which an attempt is made to put the subject's brain in a steady state of activity by using the same type of task for an extended period, of time (typically 20-60 seconds), and then comparing the brain activation during that block with other blocks which use a different task. BOLD (Blood Oxygen Level Dependent): Refers to ...

ABSTRACTNeuroimaging allows noninvasive evaluation of the anatomy, physiology, and function of the brain. It is widely used for diagnosis, treatment planning, and treatment evaluation of neurological disorders as well as understanding functions of the brain in health and disease. Neuroimaging modalities include X-ray computed tomography (CT), magnetic resonance imaging (MRI), single photon emis...