This review gives a brief description on the skin and its essential functions, damages or injury which are common to the skin and the role of skin substitute to replace the functions of the skin soon after an injury. Skin substitutes have crucial role in the management of deep dermal and full thickness wounds. At present, there is no skin substitute in the market that can replace all the functi...

The biological effects of far-infrared ray (FIR) on whole organisms remain poorly understood. The aim of our study was to investigate not only the hyperthermic effect of the FIR irradiation, but also the biological effects of FIR on wound healing. To evaluate the effect of FIR on a skin wound site, the speed of full-thickness skin wound healing was compared among groups with and without FIR usi...

wound is a break in the outer layer of skin. there are several different methods to provoke wound healing process, consisting topically or orally administration of medicinal drugs or herbal remedies. persian shallot, allium hirtifolium which belongs to the same genus of garlic,naturally grows in different parts of iran. in this study, we have avaluated the wound healing activity of hydro-alcoho...

Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of...

In the last decade, a new class of natural biomaterials derived from de-fatted soybean flour processed by either thermoset or extraction procedures has been developed. These biomaterials uniquely combine adaptability to various clinical applications to proven tissue regeneration properties. In the present work, the biomaterials were formulated either as hydrogel or as paste formulation and thei...

Data from the National Nursing Home Survey, 2004. In 2004, about 159,000 current U.S. nursing home residents (11%) had pressure ulcers. Stage 2 pressure ulcers were the most common. Residents aged 64 years and under were more likely than older residents to have pressure ulcers. Residents of nursing homes for a year or less were more likely to have pressure ulcers than those with longer stays. O...

The use of human skin models is a widely accepted approach for studying biology. These include organotypic systems reconstructed from cells as well based on discarded surgical tissue. Cell-based are time-consuming to set up and maintain, unable fully recapitulate the differentiated architecture skin, typically lack minor cell populations. Traditional full-thickness prepared excised tissue colle...