نتایج جستجو برای: friedländer hetero
تعداد نتایج: 5027 فیلتر نتایج به سال:
The tight correlation between the clinical potency and the D2R blocking action of antipsychotic medications suggests that dopamine hyperactivity plays a significant role in psychosis. Clozapine, one of the most effective antipsychotic drugs, has been shown to display moderate affinity for various neurotransmitter receptors, including the dopamine D1 and D2 receptors; however, the exact mechanis...
Clinical application of induced pluripotent stem cells (iPS) in autologous settings has just begun. To overcome the high time and cost barriers in the individual production of autologous iPS, the use of allogeneic iPS with a homozygous human leukocyte antigen (HLA) haplotype (HLA-homo HP) has been proposed. Cord blood transplantation (CBT) is a suitable model for evaluating the allogeneic immun...
Chaotic dynamics can be quite heterogeneous in the sense that some regions are unstable more directions than other regions. When trajectories wander between these regions, is complicated. We say a chaotic invariant set when arbitrarily close to each point of there different periodic points with numbers dimensions. call such chaos (or hetero-chaos), While we believe it common for physical system...
Four independent mol-ecules comprise the asymmetric unit of the title co-crystal, C(10)H(9)N(3)·C(7)H(5)NO(4), two for each component. Small conformational differences are noted for the benzoic acid derivatives, notably in the twists of the carb-oxy-lic acid residue out of the plane of the benzene ring to which it is connected [torsion angles = 167.62 (17) and 174.54 (17)°]. In the aniline deri...
The preparation of (hetero)arylamines has been significantly advanced by developments in transition metal-catalyzed Csp2–N coupling (e.g., Buchwald–Hartwig, Chan–Lam, and Ullmann couplings). As a complement to these strategies, our group recently demonstrated the reductive arylboronic acids nitro compounds, initially nitro(hetero)arenes more nitromethane, an organophosphorus-catalyzed method op...
To meet the performance requirements of low power mobile devices, a device with high ION/IOFF ratio at low-VDD is needed. TFETs are gaining popularity due to their subthreshold slope and transconductance compared MOSFETs. However, silicon-based have on-state current, which limits use in high-performance applications. overcome this limitation, using narrower band gap material like Ge can increas...
An efficient access to the tetracyclic-fused quinoline systems, 12-phenylbenzo[6,7]oxepino[3,4-b]quinolin-13(6H)-one derivatives 4a-l, is described, involving the intramolecular Friedel-Crafts acylation reaction of 2-(phenoxymethyl)-4-phenylquinoline-3-carboxylic acid derivatives 3a-l aided by the treatment with PPA (polyphosphoric acid) or Eaton's reagent. The required starting compound (2) wa...
A Silicon tunnel FET with Si1-x Gex source is investigated and optimized for improved performance. In order to optimize the device performance, Germanium mole fraction and the length of the SiGe region is varied and the optimum values are obtained. Moreover, the source/channel hetero-junction is assumed graded. The grading distance is varied from zero (abrupt hetero-junction) to total channel l...
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