The palladium-catalyzed oxidation of glucopyranosides has been investigated using relativistic density functional theory (DFT) at ZORA-BLYP-D3(BJ)/TZ2P. complete Gibbs free energy profiles for the secondary hydroxy groups C2, C3, and C4 were computed methyl beta-glucoside carba-beta-glucoside. Both computations experiments on carba-glucosides demonstrate crucial role ring oxygen in C3 regiosele...

JAR malignant trophoblast cells produce a free alpha subunit in addition to an alpha combined with beta subunit as hCG. The free alpha is larger by gel chromatography and SDS-PAGE than combined alpha and is unable to associate with beta subunit to form hCG. A tryptic fragment, representing amino acid residues 36-42, derived from free alpha was larger than the corresponding fragment from combine...

The syntheses of some new sugar-based monocyclic beta-lactams possessing several other functionalities in addition to the carbohydrate moiety are described. The key step was the Staudinger [2+2] cycloaddition of chiral carbohydrate Schiff base 5 with phthalimidoacetyl chloride to yield the sugar-based monocyclic beta-lactam 6 as a single isomer. Treatment of protected beta-lactams 6 and 8 with ...

Background Down syndrome screening at first-trimester may cause a higher false positive rate in pregnant patients who have undergone assisted reproductive technologies (ART). Combining the second largest series of biophysical and biochemical tests in the first trimester of pregnancy after ART is mentioned in few studies. MaterialsAndMethods Ghisoni et al explored that NT measurement between ART...

we report a spontaneous unilateral live tubal twin pregnancy in a patient with a history of previous ectopic pregnancy (ep) and tubal surgery. transvaginal ultrasound showed one pregnancy sac containing two fetal poles with cardiac activity, which appeared to be sited within the right adnexum. the right tubal ep was removed by salpingectomy. ultrasound findings of suspected adnexal mass and fre...

BACKGROUND Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone that exists in multiple forms. Immunoassays commonly used in clinical laboratories measure intact hCG, total beta hCG (intact hCG + hCG free beta-subunit), and/or hCG free beta-subunit. Measurement of serum concentrations of hCG is useful for confirmation and monitoring of pregnancy, diagnosis of trophoblastic...

We have studied maternal serum free beta-hCG and PAPP-A, and fetal nuchal translucency (NT) in a series of 46 cases of fetal Turner's syndrome, 13 cases of other sex chromosomal anomalies and compared these with 947 control pregnancies in the first trimester. In cases of Turner's syndrome (45,X) the median fetal NT was significantly higher than in controls (4.76 MoM), the median PAPP-A was sign...

In this paper, we investigate the homogeneous and isotropic flat FLRW Universe in logarithmic form of $f\left( Q\right) $ gravity, where $% Q is non-metricity scalar, specifically, =\alpha +\beta \log \left( $, $\alpha $\beta are free model parameters. study, consider a parametrization Hubble parameter as $H\left( z\right) =\eta \left[ (z+1)^{-\gamma }+1\right] $\gamma $\eta model/free paramete...