IN recent years there has been increasing interest in the clinical application of spatial vectorcardiography. Some comparative studies have indicated that the vectorcardiogram may be significantly superior to the conventional scalar electrocardiogram in the diagnosis of myocardial infarction and ventricular hypertrophy." 2 The Frank lead system3 has many theoretical advantages over the older ve...

Frank Ruddle, a pioneer in science and versatile in human gene mapping, transgenic technology, and several other fields in biology, has left a significant legacy. Frank was born August 19, 1929, in West New York, New Jersey, to parents who emigrated from the United Kingdom. He dropped out of high school to join the Air Force, where he served with distinction from 1946 to 1949. Like many other v...

prize. Only the older practitioners can recall the furore of hope aroused by the announcement of Professor Koch's claims for his tuberculin, but Sir Douglas Powell was the one English physician to be accorded a small amount to bring back from his visit to Berlin. As Frank Wethered was then acting as his assistant he was charged with the carrying out .of the method, and so the writer was enabled...