There is no uniformly accepted clinical definition for congestive heart failure (CHF), although criteria have been published by various groups. There is also no reference standard for CHF, although left ventricular ejection fraction (LVEF) gives a quantitative assessment of systolic function and is useful in predicting prognosis. To determine the relationship between LVEF and clinically diagnos...

Medicine, University of Massachusetts Medical School, Worcester, MA; National Heart, Lung, and Blood Institute and Boston University’s Framingham Heart Institute, Framingham, MA; Division of Quantitative Health Sciences, Department of Medicine, University of Massachusetts Medical School, Worcester, MA; and Evans Center for Interdisciplinary Biomedical Research, Boston University School of Medic...

Sekar Kathiresan, Christopher Newton-Cheh, Robert E. Gerszten* a Cardiology Division and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA b Program in Medical and Population Genetics, Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA, USA c National Heart, Lung, and Blood Institu...

OBJECTIVE To determine the extent to which the Framingham function predicts the risk of coronary heart disease (CHD) in Aboriginal people. DESIGN AND SETTING Cohort study in an Aboriginal community in the Northern Territory. PARTICIPANTS 687 Aboriginal people aged 20-74 years were followed up from a baseline examination in 1992-1995 through to 31 December 2003. MAIN OUTCOME MEASURE First ...

PURPOSE/INTRODUCTION The Canadian Hypertension Education Program (CHEP) has identified blood pressure (BP) control as a key target for an overall reduction in cardiovascular disease risk. The POWER survey (Physicians' Observational Work on Patient Education According to their Vascular Risk) used Framingham methodology to investigate the impact of an angiotensin-receptor-blocker-based regimen on...

Background and objectives: Coronary Heart Disease (CHD) has a high prevalence in Asian Indians & is the leading cause of morbidity & mortality in patients with Type 2 diabetes due to silent myocardial ischemia. This needs early cardio vascular assessment through non invasive tests e.g. Treadmill Test (TMT) & Framingham 10-year CHD risk in addition to periodical clinical examination & resting el...

The aim of this study is to determine the risk factors obstructive sleep apnea (OSA) and cardiovascular diseases (CVD) in adult patients with Type 2 diabetes. In cross-sectional study, data have been collected from 228 type diabetes by using "Patient Information Form," "Berlin Survey," "Framingham Risk Score" between March 3 July 15, 2016. OSA level affecting were assessed study. Gender, Framin...

BACKGROUND Framingham-based and Reynolds Risk scores for cardiovascular disease (CVD) prediction have not been directly compared in an independent validation cohort. METHODS AND RESULTS We selected a case-cohort sample of the multiethnic Women's Health Initiative Observational Cohort, comprising 1722 cases of major CVD (752 myocardial infarctions, 754 ischemic strokes, and 216 other CVD death...

Aims: Aortic calcification is a major risk factor for death from cardiovascular disease. We investigated the relationship between mortality and the composite markers of number, size, morphology and distribution of calcified plaques in the lumbar aorta. Methods: 308 postmenopausal women aged 48-76 were followed for 8.3±0.3 years, with deaths related to any cardiovascular disease,, cancer, or , a...