نتایج جستجو برای: fndc5

تعداد نتایج: 325  

2016
Maryam Esfahani Mostafa Baranchi Mohammad Taghi Goodarzi

Department of Clinical Biochemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, IR Iran Department of Physical Education and Sports Sciences, Tarbiat Modares University, Tehran, IR Iran Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran Corresponding author: Mohammad Taghi Goodarzi, Hamadan University of Medical Sciences, ...

Background: Diabetes is one of the most prevalent metabolic diseases. Irisin (FNDC5 protein) is involved in the new strategy of combating type 2 diabetes. In the liver, the antidiabetic mechanism of silymarin at the molecular level is unknown. This study investigated the effects of silymarin on irisin and the related gene expression and oxidative stress status in the liver of type 2 diabetic ra...

2014
María Pardo Ana B. Crujeiras María Amil Zaida Aguera Susana Jiménez-Murcia Rosa Baños Cristina Botella Rafael de la Torre Xavier Estivill Ana B. Fagundo Jose M. Fernández-Real José C. Fernández-García Gema Fruhbeck Javier Gómez-Ambrosi Roser Rodríguez Francisco J. Tinahones Fernando Fernández-Aranda Felipe F. Casanueva

FNDC5/irisin has been recently postulated as beneficial in the treatment of obesity and diabetes because it is induced in muscle by exercise, increasing energy expenditure. However, recent reports have shown that WAT also secretes irisin and that circulating irisin is elevated in obese subjects. The aim of this study was to evaluate irisin levels in conditions of extreme BMI and its correlation...

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