Coronary angiography is still the gold standard in the diagnosis of coronary artery disease, although its limitations in the assessment of haemodynamic severity of epicardial stenosis are widely recognised [1, 2]. In the 1990s, these limitations of angiography led to the introduction of sensorequipped guidewires measuring pressure and flow to optimise the diagnostic workup during cardiac cathet...

This paper describes a one-dimensional finite element code for debris flows developed to model the flow within a steep channel and the stopping conditions on the fan. The code allows the systematic comparison of a wide variety of previously proposed one-phase flow resistance laws using the same finite element solution method. The onedimensional depth-averaged equations of motion and the numeric...

PURPOSE Long-term intraocular pressure reduction by glaucoma drainage devices (GDDs) is often limited by the fibrotic capsule that forms around them. Prior work demonstrates that modifying a GDD with a porous membrane promotes a vascularized and more permeable capsule. This work examines the in vitro fluid dynamics of the Ahmed valve after enclosing the outflow tract with a porous membrane of e...

The mechanism which causes sarcopenia, a loss of muscle mass and strength with aging, remains unclear. Muscle mass is controlled by the net balance between protein synthesis and breakdown; however, net balance differences in the basal state do not contribute to sarcopenia. On the other hand, anabolic resistance, a reduction in muscle protein synthesis in response to protein intake, does seem to...

IN THE INTACT ANIMAL and m man, variations in the peripheral resistance to flow, and hence in the arterial pressure, are produced by variation in the size of the arterioles. The relationship between flow and pressure is complicated in the intact animal by the tact that blood is not a homogeneous fluid. Its apparent viscosity varies, being greater in large than in small vessels. Hemodynamic stud...

BACKGROUND The effect of epicardial artery stenosis on myocardial microvascular resistance remains controversial. Recruitable collateral flow, which may affect resistance, was not incorporated into previous measurements. METHODS AND RESULTS In an open-chest pig model, distal coronary pressure was measured with a pressure wire, and the apparent minimal microvascular resistance was calculated d...

AIMS To evaluate the effect of high dose stereotactic radiotherapy on the ocular blood flow of patients with uveal melanoma. METHODS Colour Doppler imaging (CDI) was used to measure blood flow velocity and vascular resistance in the ophthalmic, short posterior, and central retinal arteries of nine patients suffering from uveal melanoma. The measurements were taken before, 6 months, 1 year, an...