نتایج جستجو برای: floating drug delivery systems

تعداد نتایج: 1874819  

2013
Ashok Kumar

The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine tablets. Floating tablets of famotidine were prepared employing lipid solid dispersion spray drying technique with gelucire 50/13 and compritol 888 along with HPMC K100M, lactose, sodium bicarbonate and citric acid. The floating tablets were evaluated for uniformity of weight, hardness, friabi...

Journal: :Investigacion clinica 2012
Venkata Srikanth Meka Ambedkar Sunil Songa Sreenivasa Rao Nali Janaki Ram Battu Venkata Ramana Murthy Kolapalli

Abstract. The purpose of this research was to develop and evaluate effervescent gastric floating tablets of propranolol HCl. The oral delivery of antihypertensive propranolol HCl was facilitated by preparing an effervescent floating dosage form which could increase its absorption in the stomach by increasing the drug's gastric residence time. In the present work, effervescent floating tablets w...

Journal: Nanomedicine Journal 2017

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

Journal: Addiction and Health 2016
Abbas Pardakhty Hoda Soltani,

Novel drug delivery systems for controlled-release of opioid agonists as a long time painkillers or opioid antagonists for opium, heroin, and alcohol addiction are under development or in clinical use today. In this article, the field of “new drug delivery systems” is momentarily reviewed from the viewpoint of the marketed opioid agonists/antagonists dosage forms today.

2014
Deepak Kumar Palak Kapoor

The oral delivery of drugs having narrow absorption window in the gastro-intestinal tract is limited by poor bioavailability with conventional dosage forms due to incomplete drug release and short residence time at the time of absorption. To provide controlled delivery of drugs novel drug delivery systems have been developed. Different systems have been developed to increase the gastric residen...

Journal: :iranian journal of pharmaceutical research 0
reza masaeli dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran teherh sadat jafarzadeh kashi dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran rasoul dinarvand nanotechnology research centre, faculty of pharmacy, tehran university of medical sciences, tehran 1417614411, iran mohammadreza tahriri dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran vahid rakhshan department of anatomy, dental branch, islamic azad univesity mehdi esfandyari-manesh nanotechnology research center,tehran university of medical sciences, tehran, iran

microspheres formulated from poly (d,l-lactic-co-glycolide) (plga), a biodegradable polymer, have been extensively evaluated as a drug delivery system. in this study, the preparation, characterization and drug release properties of the plga microspheres were evaluated. simvastatin (sim)-loaded plga microspheres were prepared by oil-in-water emulsion/solvent evaporation method. the microspheres ...

Chhagan N. Patel Dashrath M. Patel Nurudin P. Jivani Rishad R. Jivani,

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

Chhagan N. Patel Dashrath M. Patel Nurudin P. Jivani Rishad R. Jivani,

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

Journal: :journal of paramedical sciences 0
afshin khavari department of hepatitis and aids, pasteur institute of iran, tehran, iran zahra orafa department of hepatitis and aids, pasteur institute of iran, tehran, iran mehrdad hashemi department of genetics, islamic azad university, tehran medical sciences branch,tehran,iran noorieh habibzadeh department of hepatitis and aids, pasteur institute of iran, tehran, iran azam bolhassani department of hepatitis and aids, pasteur institute of iran, tehran, iran

delivery of exogenous materials such as nucleic acids, peptides, proteins, and drugs into cells is an important strategy in modern cellular and molecular biology. recently, the development of gene carriers for efficient gene transfer into cells has attracted a great attention. furthermore, lack of effective drug delivery is one of the major problems of cancer chemotherapy. many physical methods...

Journal: :Journal of Biomaterials and Nanobiotechnology 2011

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