The bile salt export pump (BSEP, ABCB11) is predominantly responsible for the efflux of bile salts, and disruption of BSEP function is often associated with altered hepatic homeostasis of bile acids and cholestatic liver injury. Accumulating evidence suggests that many drugs can cause cholestasis through interaction with hepatic transporters. To date, a relatively strong association between dru...

introduction: the fate of xenobiotics that is present, increasing day by day. the increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. methods: the present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by panax ginseng ...

AIM This study is aimed to investigate differences between cognitive, language and motor development of high-risk infants related to birth weight and gestational age. MATERIAL AND METHODS One hundred sixty high-risk infants who were born 32 weeks, 1 500 gr and below included in this study. According to corrected age, 58 infants were 1 month, 72 were at 4 months, 82 were at 8 months and 65 wer...

AIM Patent Ductus Arteriosus is an important cause of morbidity and mortality in preterms. As birth weight decrease, risks increase. Main aim of our study is to emphasize the effectiveness and safety of percutaneous PDA closure even in extremely low birth infants. MATERIALS AND METHODS In our center between the dates June 2014-June 2016, PDA of 10 patients less than 1,000 gr were closed percu...

The efficacy and safety of intermittent hypoxia training (IHT) were investigated in healthy, 60- to 74-yr-old men. Fourteen men (Gr 1) who routinely exercised daily for 20 to 30 min were compared with 21 (Gr 2) who avoided exercise. Their submaximal work-load power values before the IHT training were 94 +/- 3.7 and 66 +/- 3.1, respectively. Before and after 10 days of IHT, the ventilatory respo...

Abstract Octopus fishing activity have been established in Ampana Waters and surrounding areas since the 1990s. The goal of this research is to examine octopus fishery waters its surroundings. methodology used study are CPUE Length-based assessment which includes some analysis catch per unit effort, season, size structure, weigh distribution, length-weight relationship, ground, gear operation s...

In various tissues, glucocorticoids (GCs) are known to downregulate glucose transport systems; however, their effects on glucose transporters (GLUTs) in the placenta of a diabetic rat are unknown. Glucocorticoid hormone action within the cell is regulated by the glucocorticoid receptor (GR). Thus, this study was designed to investigate the relationship between GR and glucose transporter express...

In its most schematic form, the Weyl character formula can be expressed by the ratio P Q of two multinomials P ≡ a(1)+a(2) . . . a(D) and Q ≡ b(1)+b(2) . . . b(D) where D is the order of Weyl groupW (Gr) for a Lie algebra Gr of rank r. Each and every one of a(k)’s and b(k)’s is obtained by the action of a Weyl reflection, i.e. an element of W (Gr). We, instead, show that there is a way to obtai...

The purpose of this study was to determine the growth cocoa seedlings on Ultisol soil treated with cow dung compost. This research conducted in piyo garden, Batanghar University, Jambi Campus II. environmental design used a completely randomized (CRD) and treatment compost which consisted 4 treatments: K0 = no (control), K1 100 gr/polybag dung, K2 150 K3 200 gr/poly bag dung. Observational data...